1. Advanced Biology Genetics
Chapter Review
Advanced Biology
Genetics

2. Mendel and Basic Genetics
Round 1
Mendel and Basic Genetics

3. Question 1
How many unique gametes could be produced through independent assortment by an individual with the genotype AaBBCcDdee? 8
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4. Question 2
In fruit flies red eyes are dominant to sepia eyes. If you do a cross between two flies and notice a 3:1 phenotypic ratio in the F1 generation, what does that tell you about the genotypes of P1 parents.
Both are heterozygous
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5. Question 3
A sexually reproducing has two unlinked genes, one for eye shape (E) and the other for eye color (R). Its genotype is EeRr. What are the possible genotypes that could be produced in the gametes of this organism?
ER, Er, eR, er
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6. Question 4
If you cross an individual that is homozygous recessive for a trait with an individual that is heterozygous, what is the chance of producing a homozygous recessive offspring?
50%
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7. Question 5
Black fur in mice (B) is dominant to brown fur (b). Short tails (T) are dominant to long tails (t). What fraction of the progeny of the cross BbTt × BBtt will have black fur and long tails?
1 x ½ = ½
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8. Question 6
In a cross AaBbcc x aaBBCc, what is the probability of producing offspring that are heterozygous for all traits?
½ x ½ x ½ = 1/8
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9. Question 7
Which describes the ability of a single gene to have multiple phenotypic effects?
Pleiotropy
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10. Question 8
What type of inheritance best describes the ABO blood group system?
Codominance or Multiple Alleles
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11. Question 9
Which of the following terms best describes when the phenotype of the heterozygote differs from the phenotypes of both homozygotes?
Codominance or Incomplete Dominance
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12. Question 10
Name one trait in humans that is inherited via polygenic inheritance.
Skin Color, Height, etc.
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13. Pedigrees and Chromosomal Basis of Inheritance
Round 2
Pedigrees and Chromosomal Basis of Inheritance

14. Question 1
Black fur is dominant in mice. How could you experimentally determine whether a black mouse is homozygous dominant or heterozygous for the trait?
Perform a test cross, cross the organisms with a homozygous recessive organism
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15. Question 2
What type of inheritance is most likely reflected in the pedigree below?
Dominant
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16. Question 3 What are the genotypes of individuals III-3 and IV-1?
III-3-Aa (heterozygous), IV-1-aa (homozygous recessive)
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17. Question 4
When Thomas Hunt Morgan crossed his red-eyed F1 generation flies to each other, the F2 generation included both red- and white-eyed flies. Remarkably, all the white-eyed flies were male. What was the explanation for this result?
An X-linked Trait
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18. Question 5
Red-green color blindness is a sex-linked recessive trait in humans. Two people with normal color vision have a color-blind son. What are the genotypes of the parents?
XAXa and XAY
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19. Question 6
True or False: The closer two genes are on a chromosome, the lower the probability that a crossover will occur between them.
True
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20. Question 7
New combinations of linked genes are due to which of the following?
Crossing Over
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21. Question 8
According to the chromosome map below, what two genes would have the lowest frequency of recombination?
A and G
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22. Question 9 A cell that has 2n + 1 chromosomes is referred to as
Triploid
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23. Question 10
In humans, male-pattern baldness is controlled by an autosomal gene that occurs in two allelic forms. Allele Hn determines nonbaldness, and allele Hb determines pattern baldness. In males, because of the presence of testosterone, allele Hb is dominant over Hn. If a man and woman both with genotype HnHb have a son, what is the chance that he will eventually be bald?
75%
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24. Round 3
Double Point Round

25. Question 1
Of the following human aneuploidies, which is the one that generally has the most severe impact on the health of the individual?
47, +21 or 47, XXX
47, +21
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26. Question 2
Mitochondrial DNA is primarily involved in coding for proteins needed for electron transport. If a mutation was passed on that resulted in a disease related to electron transport, who was the disease inherited from?
mother
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27. Question 3
One possible result of chromosomal breakage is for a fragment to join a nonhomologous chromosome. What is this alteration called?
translocation
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28. Question 4
Determine the sequence of genes along a chromosome based on the following recombination frequencies: A—B, 8 map units; A—C, 28 map units; A—D, 25 map units; B—C, 20 map units; B—D, 33 map units.
D-A-B-C
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29. Question 5
A man with hemophilia (a recessive, sex-linked condition) has a daughter of normal phenotype. She marries a man who is normal for the trait. What is the probability that a daughter of this mating will be a hemophiliac? That a son will be a hemophiliac? If the couple has four sons, what is the probability that all four will be born with hemophilia?
0, ½, 1/16
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