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Clinical efficacy of endovascular therapy for patients with critical limb ischemia attributable to pure isolated infrapopliteal lesions  Osamu Iida, MD,

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Presentation on theme: "Clinical efficacy of endovascular therapy for patients with critical limb ischemia attributable to pure isolated infrapopliteal lesions  Osamu Iida, MD,"— Presentation transcript:

1 Clinical efficacy of endovascular therapy for patients with critical limb ischemia attributable to pure isolated infrapopliteal lesions  Osamu Iida, MD, Yoshimitsu Soga, MD, Yasutaka Yamauchi, MD, Keisuke Hirano, MD, Daizo Kawasaki, MD, Terutoshi Yamaoka, MD, Mitsuyoshi Takahara, MD, Masaaki Uematsu, MD, PhD  Journal of Vascular Surgery  Volume 57, Issue 4, Pages e1 (April 2013) DOI: /j.jvs Copyright © Terms and Conditions

2 Fig 1 A, Freedom from major adverse limb events with perioperative death (MALE+POD) after angioplasty for 1057 critical ischemic limbs because of pure isolated infrapopliteal lesions. Overall freedom from MALE+POD was 82 ± 1%, 79 ± 2%, and 74 ± 2% at 1, 3, and 5 years, respectively. B, Amputation-free survival (AFS) after angioplasty for 884 patients with critical limb ischemia (CLI) due to pure isolated infrapopliteal lesions. AFS was 71 ± 2%, 51 ± 2%, and 37 ± 3% at 1, 3, and 5 years, respectively. SE, Standard error. Journal of Vascular Surgery  , e1DOI: ( /j.jvs ) Copyright © Terms and Conditions

3 Fig 2 Risk stratification of major adverse limb events with perioperative death (MALE+POD) based on multivariable logistic analysis. Patients were assigned to groups based on the number of multivariable risk factors. Freedom from MALE+POD was lower in the higher-risk groups (1-year rates by number of risk factors: 94% for 0-1; 86% for 2; 75% for 3; 58% for 4; and 18% for 5 factors, respectively; P < .001). Journal of Vascular Surgery  , e1DOI: ( /j.jvs ) Copyright © Terms and Conditions

4 Fig 3 Risk stratification of amputation-free survival (AFS) based on multivariable logistic analysis. Patients were assigned to groups based on the number of multivariable risk factors. AFS was lower in the higher-risk groups (1-year rates by number of factors: 90% for 0-1; 82% for 2; 71% for 3; 57% for 4; 38 % for 5; and 3% for 6-8 factors, respectively; P < .001). Journal of Vascular Surgery  , e1DOI: ( /j.jvs ) Copyright © Terms and Conditions

5 Supplementary Fig 1 (online only)
Overall survival after angioplasty for the 884 patients with critical limb ischemia (CLI) because of pure isolated infrapopliteal lesions. Overall survival was 78 ± 1%, 59 ± 2%, and 43 ± 2% at 1, 3, and 5 years, respectively. SE, Standard error. Journal of Vascular Surgery  , e1DOI: ( /j.jvs ) Copyright © Terms and Conditions

6 Supplementary Fig 2 (online only)
Limb salvage rate after angioplasty in 1057 critical ischemic limbs. Limb salvage rate was 89 ± 2%, 86 ± 2%, and 85 ± 2% at 1, 3, and 5 years, respectively. Almost all major amputations were performed before 1 year. SE, Standard error. Journal of Vascular Surgery  , e1DOI: ( /j.jvs ) Copyright © Terms and Conditions

7 Supplementary Fig 3 (online only)
Freedom from any reintervention. Freedom from any reintervention including minor or major reintervention was 66 ± 1%, 56 ± 1%, and 47 ± 2% at 1, 3, and 5 years, respectively. SE, Standard error. Journal of Vascular Surgery  , e1DOI: ( /j.jvs ) Copyright © Terms and Conditions

8 Supplementary Fig 4 (online only)
Major adverse limb event (MALE)-free survival. MALE-free survival was 66 ± 2%, 49 ± 2%, and 33 ± 3% at 1, 3, and 5 years, respectively. SE, Standard error. Journal of Vascular Surgery  , e1DOI: ( /j.jvs ) Copyright © Terms and Conditions

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