1. Anaesthesia and myocardial ischaemia/reperfusion injury
J. Fräßdorf, S. De Hert, W. Schlack 
British Journal of Anaesthesia 
Volume 103, Issue 1, Pages (July 2009)
DOI: /bja/aep141
Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

2. Fig 1
Schematic overview of the signal transduction of anaesthetic-induced cardioprotection and possible interactions through anaesthetic drugs or drugs used frequently in the perioperative period. Akt, protein kinase B; cAMP, cyclic adenosine monophosphate; ERK1, extracellular regulated kinase 1; mitoKATP channels, mitochondrial adenosine triphosphate sensitive potassium channels; NO, nitric oxide; eNOS, endothelial nitric oxide synthetase; PKC, protein kinase C; PLC, phospholipase C; PKA, protein kinase A; mitoPTP, mitochondrial permeability transition pore; BKCa channel, large conductance Ca2+-sensitive K+ channel; Cyt, cytochrome C; I, II, III, IV, V, mitochondrial respiratory chain; SR, sarcoplasmatic reticulum; MEK 1, mitogen-activated protein kinase 1; PI3K, phosphoinositide 3-kinases; PDK-1, 3-phosphoinositide-dependent kinase 1; GS, stimulatory G-protein.
British Journal of Anaesthesia  , 89-98DOI: ( /bja/aep141)
Copyright © 2009 British Journal of Anaesthesia Terms and Conditions