1. Characterizing geometrical accuracy in clinically optimised 7T and 3T magnetic resonance images for high-precision radiation treatment of brain tumours 
Jurgen Peerlings, Inge Compter, Fiere Janssen, Christopher J. Wiggins, Alida A. Postma, Felix M. Mottaghy, Philippe Lambin, Aswin L. Hoffmann 
Physics and Imaging in Radiation Oncology 
Volume 9, Pages (January 2019)
DOI: /j.phro
Copyright © 2018 The Authors Terms and Conditions

2. Fig. 1
Overview of 3D data acquisition and analyses. XYZ-coordinates are determined on CT and MR images (1a.), and based on product characteristics of the CIRS’ phantom model 603A (1b.). Global MAD (2a.) is based on distances with 2 variable grid-intersection points (*example given for 1 intersection but applies for all points). Local MAD (2b.) is based on distances between magnetic field isocentre and 1 variable grid-intersection points. Displacements vectors (3a.) are determined between the measured and reference coordinates of each individual data-point and indicate the relative 3D geometrical distortion.
Physics and Imaging in Radiation Oncology 2019 9, 35-42DOI: ( /j.phro )
Copyright © 2018 The Authors Terms and Conditions

3. Fig. 2
Absolute differences in Euclidian distance between the measured and reference dataset (grey dot) relative to the unique distances found in the reference dataset, observed within CT (a), MP2RAGE (b), T2-SPACE (c), T2-SPACE FLAIR (d), T1-GRE (e), 3D TFE (f), T2-VISTA (g), T2-VISTA FLAIR (h), T1-FFE (i). The overall geometric distortion was quantified by MADGlobal (±SD) (blue square). The 95% confidence interval (CI95) is shown as the dotted horizontal line. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
Physics and Imaging in Radiation Oncology 2019 9, 35-42DOI: ( /j.phro )
Copyright © 2018 The Authors Terms and Conditions

4. Fig. 3
MADLocal values (±SD) relative to the distance from the magnetic isocentre at 7T (a) and 3T (b) MRI, both relative to CT (black square). Presented 7T MR sequence include MP2RAGE (green circle), T2-SPACE (purple diamond), T2-SPACE FLAIR (orange downward triangle), and T1-GRE (blue upward triangle). The same colour- and shape-code was used for the equivalent 3T sequences, 3D TFE, T2-VISTA, T2-VISTA FLAIR, and T1-FFE, respectively. The dotted horizontal line represents the 1 mm-acceptability level required for spatially reliable RTP. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
Physics and Imaging in Radiation Oncology 2019 9, 35-42DOI: ( /j.phro )
Copyright © 2018 The Authors Terms and Conditions

5. Fig. 4
Distortion maps of MP2RAGE on 7T MRI (a) and 3D TFE on 3T MRI (b) measured in the axial plane nearest the magnetic isocentre (Y = 0), in the coronal plane (Z = 0), and in the sagittal plane (X = 0).
Physics and Imaging in Radiation Oncology 2019 9, 35-42DOI: ( /j.phro )
Copyright © 2018 The Authors Terms and Conditions

6. Supplementary figure 1
Physics and Imaging in Radiation Oncology 2019 9, 35-42DOI: ( /j.phro )
Copyright © 2018 The Authors Terms and Conditions

7. Supplementary figure 2
Physics and Imaging in Radiation Oncology 2019 9, 35-42DOI: ( /j.phro )
Copyright © 2018 The Authors Terms and Conditions

8. Supplementary figure 3
Physics and Imaging in Radiation Oncology 2019 9, 35-42DOI: ( /j.phro )
Copyright © 2018 The Authors Terms and Conditions

9. Supplementary figure 4
Physics and Imaging in Radiation Oncology 2019 9, 35-42DOI: ( /j.phro )
Copyright © 2018 The Authors Terms and Conditions

10. Supplementary figure 5
Physics and Imaging in Radiation Oncology 2019 9, 35-42DOI: ( /j.phro )
Copyright © 2018 The Authors Terms and Conditions