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Underestimation of Liver-Related Mortality in the United States

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1 Underestimation of Liver-Related Mortality in the United States
Sumeet K. Asrani, Joseph J. Larson, Barbara Yawn, Terry M. Therneau, W. Ray Kim  Gastroenterology  Volume 145, Issue 2, Pages e2 (August 2013) DOI: /j.gastro Copyright © 2013 AGA Institute Terms and Conditions

2 Figure 1 Liver-related mortality, Percent of overall liver related deaths in 2008 by the predefined categories (CDC, expanded (exclusive of CDC), viral hepatitis and hepatobiliary) as stratified by race. The sum of all the rates comprises the updated estimate of liver-related mortality by race. Adjusted to US Census 2000 population, only individuals older than 15 years at risk. AA, African American; AI/AN, American Indian and Alaska Native. Gastroenterology  , e2DOI: ( /j.gastro ) Copyright © 2013 AGA Institute Terms and Conditions

3 Figure 2 Liver-related mortality in the United States, 1979−2008. Separate trend lines for viral hepatitis, liver cancer, and expanded liver (CDC definition and other causes of liver-related mortality) are provided. The updated estimate includes these 3 diagnosis groups. As a comparison, the current CDC estimate is provided (black line). Adjusted to US Census 2000 population, only individuals older than 15 years at risk. Gastroenterology  , e2DOI: ( /j.gastro ) Copyright © 2013 AGA Institute Terms and Conditions

4 Figure 3 Liver-related deaths by era. Era 1: 1979−1988; era 2: 1989−1998; era 3: 1999−2008. Adjusted rates per 100,000 are provided by category (CDC, expanded [exclusive of CDC], viral hepatitis, and hepatobiliary malignancies). Adjusted to US Census 2000 population, only individuals older than 15 years at risk. Gastroenterology  , e2DOI: ( /j.gastro ) Copyright © 2013 AGA Institute Terms and Conditions

5 Figure 4 Age-specific death rates (per 100,000 persons) for liver disease-related mortality in 10-year age groups in the United States, 1979−2008. Gastroenterology  , e2DOI: ( /j.gastro ) Copyright © 2013 AGA Institute Terms and Conditions

6 Figure 5 Age- and sex-adjusted death rates (per 100,000 persons) in Olmsted County, Minnesota vs national estimate, 1999−2008. Adjusted to US Census 2000 population, only individuals older than 15 years at risk. Gastroenterology  , e2DOI: ( /j.gastro ) Copyright © 2013 AGA Institute Terms and Conditions


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