1. Reproductive Biomedicine & Society Online
Comparative economic study of the use of corifollitropin alfa and daily rFSH for controlled ovarian stimulation in older patients: Cost-minimization analysis based on the PURSUE study 
Gorka Barrenetxea, Juan Antonio García-Velasco, Belén Aragón, Jordi Osset, Max Brosa, Noemí López-Martínez, Buenaventura Coroleu 
Reproductive Biomedicine & Society Online 
Volume 5, Pages (April 2018)
DOI: /j.rbms
Copyright © 2018 The Author(s) Terms and Conditions

2. Fig. 1
Results of primary analysis: total pharmacological cost per cycle of corifollitropin alfa versus recombinant follicle-stimulating hormone (rFSH).
COS, controlled ovarian stimulation.
aAverage pharmacological cost of Puregon®, Gonal-F®, Bemfola® and Ovaleap®.
bBemfola.
cOvaleap.
Reproductive Biomedicine & Society Online 2018 5, 46-59DOI: ( /j.rbms )
Copyright © 2018 The Author(s) Terms and Conditions

3. Fig. 2
Cost of treatment outcomes (oocytes recovered) based on the efficacy outcomes of the PURSUE study (Boostanfar et al., 2015).
ICSI, intracytoplasmic sperm injection.
Average cost, taking into account the efficacy outcomes for corifollitropin alfa in both groups.
Recombinant follicle-stimulating hormone (rFSH) cost, average pharmacological cost of Puregon®, Gonal-F®, Bemfola® and Ovaleap®.
Reproductive Biomedicine & Society Online 2018 5, 46-59DOI: ( /j.rbms )
Copyright © 2018 The Author(s) Terms and Conditions

4. Fig. 3
Results of alternative analysis 1: private sector and total costs.
Recombinant follicle-stimulating hormone (rFSH), average pharmacological cost of Puregon®, Gonal-F®, Bemfola® and Ovaleap®.
Reproductive Biomedicine & Society Online 2018 5, 46-59DOI: ( /j.rbms )
Copyright © 2018 The Author(s) Terms and Conditions

5. Fig. 4
Results of alternative analysis 2: Spanish National Health System and total costs.
Recombinant follicle-stimulating hormone (rFSH), average pharmacological cost of Puregon®, Gonal-F®, Bemfola® and Ovaleap®.
Reproductive Biomedicine & Society Online 2018 5, 46-59DOI: ( /j.rbms )
Copyright © 2018 The Author(s) Terms and Conditions