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Volume 72, Issue 12, Pages 1423-1426 (December 2007)
Thiazide diuretic monotherapy for hypertension: Diuretic's dark side just got darker B.H. Rovin, L.A. Hebert Kidney International Volume 72, Issue 12, Pages (December 2007) DOI: /sj.ki Copyright © 2007 International Society of Nephrology Terms and Conditions
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Figure 1 Association of BP reduction with risk reduction for fatal and non-fatal myocardial infarction in randomized trials of angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) against a comparator therapy (diuretic, β-blocker, or calcium channel blocker). The fitted lines represent the summary meta-regressions for the outcomes of the ACEI trials (lower line) and the ARB trials (upper line). See Boxes 1, 2, and 3 for further analysis. The ACEI trials' meta-regression line can be regarded as the 'optimal ACEI therapy' line, because all trials, except ALLHAT, used ACEI optimally (with diuretic, if needed). (Adapted from ref. 8.) Kidney International , DOI: ( /sj.ki ) Copyright © 2007 International Society of Nephrology Terms and Conditions
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