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Evaluation of Techniques for Lung Transplantation Following Donation After Cardiac Death  Gregory I. Snell, MD, Takahiro Oto, MD, Bronwyn Levvey, B Ed.

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Presentation on theme: "Evaluation of Techniques for Lung Transplantation Following Donation After Cardiac Death  Gregory I. Snell, MD, Takahiro Oto, MD, Bronwyn Levvey, B Ed."— Presentation transcript:

1 Evaluation of Techniques for Lung Transplantation Following Donation After Cardiac Death 
Gregory I. Snell, MD, Takahiro Oto, MD, Bronwyn Levvey, B Ed Stud, Robin McEgan, CCP, Mark Mennan, CCP, Takao Higuchi, MD, Leif Eriksson, MD, Trevor J. Williams, MD, Franklin Rosenfeldt, MD, PhD  The Annals of Thoracic Surgery  Volume 81, Issue 6, Pages (June 2006) DOI: /j.athoracsur Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 A schema outlining the seven donations after cardiac death donor lung retrieval, preservation, and evaluation experiments. The timing bars are not exactly to scale. (Solid line = stand-off time; dashed line = rig evaluation; braided line = cold ischemia; solid/dash line = procedure time; down arrows = blood flush evaluation.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Donation after cardiac death donor lung outcome measures versus time on the ex-vivo perfusion rig. (a) The left atrial pO2 at FiO2 0.5 (except for last 2 marked time points, which are as marked). (b) The pulmonary artery pressure (PAP) versus time. (c) The pulmonary vascular resistance (PVR) versus time. (Diamond = experiment 1; box = experiment 2; triangle = experiment 3; cross = experiment 4; asterisk = experiment 5; circle = experiment 6; hatch mark = experiment 7.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Blood flush pO2 versus ex-vivo perfusion rig pO2. Boxes indicate individual points. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions


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