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The consequences of an outbreak of multidrug-resistant Pseudomonas aeruginosa among patients treated for critical leg ischemia  Maria Söderström, MD,

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Presentation on theme: "The consequences of an outbreak of multidrug-resistant Pseudomonas aeruginosa among patients treated for critical leg ischemia  Maria Söderström, MD,"— Presentation transcript:

1 The consequences of an outbreak of multidrug-resistant Pseudomonas aeruginosa among patients treated for critical leg ischemia  Maria Söderström, MD, Pirkka Vikatmaa, MD, Mauri Lepäntalo, MD, PhD, Pekka-Sakari Aho, MD, PhD, Elina Kolho, MD, PhD, Tuija Ikonen, MD, PhD  Journal of Vascular Surgery  Volume 50, Issue 4, Pages (October 2009) DOI: /j.jvs Copyright © 2009 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Kaplan-Meier curves demonstrate amputation-free survival in the multidrug-resistant Pseudomonas aeruginosa (MDR Pa) group and in the control group. At 1 year after the bypass, patients with MDR Pa showed significantly decreased amputation-free survival (P = .020; χ2 test). After 5-year follow-up, the amputation-free survival was poor in both groups (P = .144, Kaplan-Meier analysis). The standard error is <10% at each time point in the curve. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2009 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Survival rates after infrainguinal bypass surgery due to critical limb ischemia in the multidrug-resistant Pseudomonas aeruginosa (MDR Pa) group and in the control group demonstrated by Kaplan-Meier analysis. The survival was lower in the MDR Pa group at 1 year compared with the control group, but the difference did not reach statistical significance (P = .063). Both groups showed low survival rates in long-term follow-up (P = .302). The standard error is <10% at each time point in the curve. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2009 Society for Vascular Surgery Terms and Conditions

4 Fig 3 Kaplan-Meier curves demonstrate the leg salvage. The leg salvage rate was lower in the multidrug-resistant Pseudomonas aeruginosa (MDR Pa) group at 1 year (P = .078) and at 5 years after infrainguinal bypass surgery (P = .126) compared with the control group, but the differences were not significant. The standard error is <10% at each time point in the curve. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2009 Society for Vascular Surgery Terms and Conditions

5 Fig 4 Kaplan-Meier life-table curves demonstrate secondary patency in the multidrug-resistant Pseudomonas aeruginosa (MDR Pa) group and in the control group. The difference in the secondary patency rate between the MDR Pa group and the control group was not significant (P = .149). Graft patency was monitored until 1 year after the infrainguinal bypass surgery, determined by clinical examination, duplex Doppler imaging, and the ankle-brachial index. The standard error is <10% at each time point in the curve. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2009 Society for Vascular Surgery Terms and Conditions

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