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The ABCs of Pharmacogenomics in Clinical Practice

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Presentation on theme: "The ABCs of Pharmacogenomics in Clinical Practice"— Presentation transcript:

1 The ABCs of Pharmacogenomics in Clinical Practice

2 This program will include a discussion of data that were presented in abstract form. These data should be considered preliminary until published in a peer-reviewed journal.

3 Unmet Needs in the Treatment of MDD

4 What Is Pharmacogenomics/Pharmacogenetics (PGx)?

5 PGx Testing in Psychiatry

6 Using PGx Testing to Select MDD Treatment Meta-Analysis of Studies

7 GUIDED Trial of PGx Testing vs Treatment as Usual Study Design

8 GUIDED Trial of PGx Testing vs Treatment as Usual Efficacy Outcomes

9 GUIDED Trial of PGx Testing vs Treatment as Usual Subset Analysis

10 Practical Application of PGx Testing

11 Metabolizer Phenotypes

12 Examples of Pharmacogenomic Decision Support Tools in Psychiatry

13 Differences in PGx Testing Platforms

14 Clinical Utility of PGx Testing

15 Potential for Improving Utility of PGx Testing

16 Cost-Effectiveness of PGx in Psychiatric Disorders

17 Does PGx Have a Role in Psychiatric Practice?

18 Does PGx Have a Role in Psychiatric Practice? (cont)

19 PRIME Care Study of PGx Testing in US Veterans Study Design

20 Personalized Medication Decision Factors

21 Conclusions

22 Abbreviations

23 Abbreviations (cont)


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