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Radiation-Induced Pulmonary Veno-occlusive Disease

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Presentation on theme: "Radiation-Induced Pulmonary Veno-occlusive Disease"— Presentation transcript:

1 Radiation-Induced Pulmonary Veno-occlusive Disease
Mordechai R. Kramer, M.D., F.C.C.P, Marc Estenne, M.D., Ph.D., Neville Berkman, M.B.B.Ch., M.R.C.P, Martine Antoine, M.D., Philippe de Francquen, M.D., Alex Lipski, M.D., Danielle Jacobovitz, M.D., Joel Lafair, M.D.  CHEST  Volume 104, Issue 4, Pages (October 1993) DOI: /chest Copyright © 1993 The American College of Chest Physicians Terms and Conditions

2 FIGURE 1 Chest radiography of patient showing diffuse alveolar edema and bilateral pleural effusion. CHEST  , DOI: ( /chest ) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

3 FIGURE 2 Lung section showing extensive interstitial fibrosis w ith thickening of interalveolar septa. Alveolar spaces are filled with hemosiderin-laden macrophages (top left). Note intimal thickening of venules (bottom) (hematoxylin eosin, × 400). CHEST  , DOI: ( /chest ) Copyright © 1993 The American College of Chest Physicians Terms and Conditions

4 FIGURE 3 Section showing a typical venule with intimal proliferation and near obliteration of lumen, (elastin stain, × 400). CHEST  , DOI: ( /chest ) Copyright © 1993 The American College of Chest Physicians Terms and Conditions


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