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Published byRhoda Karen Bell Modified over 5 years ago
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New Clinical Insights Into the Pathology of Amyloidosis
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What is Amyloidosis?
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Protein Structure A Brief Review
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What Makes a Protein Amyloidogenic?
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Amyloidoses Protein Folding Disorders
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Amyloidoses Protein Folding Disorders
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What Are Amyloidoses?
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AL (Amyloid Light Chain)
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External Signs of AL Amyloidosis
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Hereditary Transthyretin Amyloidosis
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Hereditary Transthyretin Amyloidosis
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Wild-Type ATTR
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AA Amyloidosis
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ALECT2 Amyloidosis
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Diagnosis of Amyloidosis
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Diagnosis of Amyloidosis (cont)
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Clinical Suspicion of Amyloidosis
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Fine Needle Abdominal Fat Pad Biopsies
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Sensitivity of Various Organ Biopsies in the Diagnosis of Amyloidosis
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Diagnostic Algorithm for Systemic Amyloidoses
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Key Points to Consider for Amyloid Protein Typing
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Amyloid Protein Typing Challenges With Immunohistochemistry
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Proteomic Analysis to Classify Amyloidoses
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Genetic Testing
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Determining an Appropriate Treatment Plan
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Therapies in AL amyloidosis Targeting the Precursor Protein
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Therapies in AA and ALECT2 Amyloidosis
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Hereditary Transthyretin Amyloidosis Current Approaches
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Concluding Remarks
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Abbreviations
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