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Socioeconomic status and race as risk factors for cockroach allergen exposure and sensitization in children with asthma  Sampson B. Sarpong, MDa, Robert.

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Presentation on theme: "Socioeconomic status and race as risk factors for cockroach allergen exposure and sensitization in children with asthma  Sampson B. Sarpong, MDa, Robert."— Presentation transcript:

1 Socioeconomic status and race as risk factors for cockroach allergen exposure and sensitization in children with asthma  Sampson B. Sarpong, MDa, Robert G. Hamilton, PhDb, Peyton A. Eggleston, MDa, N.Franklin Adkinson, MDb  Journal of Allergy and Clinical Immunology  Volume 97, Issue 6, Pages (June 1996) DOI: /S (96) Copyright © 1996 Mosby, Inc. Terms and Conditions

2 FIG. 1 Distribution of cockroach allergen Bla g 1 and Bla g 2 in three locations of homes of 87 children with moderate to severe asthma. The limit of detection of the assay is 0.8 U/gm. Median levels of homes with detectable cockroach allergens are indicated by horizontal bars. Numbers below the dotted line indicate numbers of samples that contained less than 0.8 U/gm of fine settled dust. Journal of Allergy and Clinical Immunology  , DOI: ( /S (96) ) Copyright © 1996 Mosby, Inc. Terms and Conditions

3 FIG. 2 Rate of cockroach skin sensitivity related to levels of cockroach allergens in bedroom dust samples for Bla g 1 (A) and Bla g 2 (B). Cockroach allergen levels were significantly related to the presence of a positive skin test response (p < 0.001). Journal of Allergy and Clinical Immunology  , DOI: ( /S (96) ) Copyright © 1996 Mosby, Inc. Terms and Conditions

4 FIG. 2 Rate of cockroach skin sensitivity related to levels of cockroach allergens in bedroom dust samples for Bla g 1 (A) and Bla g 2 (B). Cockroach allergen levels were significantly related to the presence of a positive skin test response (p < 0.001). Journal of Allergy and Clinical Immunology  , DOI: ( /S (96) ) Copyright © 1996 Mosby, Inc. Terms and Conditions

5 FIG. 3 Cockroach allergen exposure analyzed by the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with exposure (p < 0.001). A significant difference in race was only seen in the middle SES (p < 0.001). Urban versus suburban residence was not significantly different in any of the three SES groups. Journal of Allergy and Clinical Immunology  , DOI: ( /S (96) ) Copyright © 1996 Mosby, Inc. Terms and Conditions

6 FIG. 3 Cockroach allergen exposure analyzed by the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with exposure (p < 0.001). A significant difference in race was only seen in the middle SES (p < 0.001). Urban versus suburban residence was not significantly different in any of the three SES groups. Journal of Allergy and Clinical Immunology  , DOI: ( /S (96) ) Copyright © 1996 Mosby, Inc. Terms and Conditions

7 FIG. 3 Cockroach allergen exposure analyzed by the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with exposure (p < 0.001). A significant difference in race was only seen in the middle SES (p < 0.001). Urban versus suburban residence was not significantly different in any of the three SES groups. Journal of Allergy and Clinical Immunology  , DOI: ( /S (96) ) Copyright © 1996 Mosby, Inc. Terms and Conditions

8 FIG. 4 Sensitization to cockroach allergen analyzed in terms of the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with cockroach sensitization (p < 0.001). A significant difference in race was seen only in the middle SES (p < 0.001). Urban versus suburban residence did not show any difference in any of the three SES groups. Journal of Allergy and Clinical Immunology  , DOI: ( /S (96) ) Copyright © 1996 Mosby, Inc. Terms and Conditions

9 FIG. 4 Sensitization to cockroach allergen analyzed in terms of the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with cockroach sensitization (p < 0.001). A significant difference in race was seen only in the middle SES (p < 0.001). Urban versus suburban residence did not show any difference in any of the three SES groups. Journal of Allergy and Clinical Immunology  , DOI: ( /S (96) ) Copyright © 1996 Mosby, Inc. Terms and Conditions

10 FIG. 4 Sensitization to cockroach allergen analyzed in terms of the subject’s SES (A), race nested within SES (B), and residence nested within SES (C). SES was significantly associated with cockroach sensitization (p < 0.001). A significant difference in race was seen only in the middle SES (p < 0.001). Urban versus suburban residence did not show any difference in any of the three SES groups. Journal of Allergy and Clinical Immunology  , DOI: ( /S (96) ) Copyright © 1996 Mosby, Inc. Terms and Conditions

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