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Intestinal Disease in Hermansky-Pudlak Syndrome: Occurrence of Colitis and Relation to Genotype
Nadeem Hussain, Martha Quezado, Marjan Huizing, David Geho, James G. White, William Gahl, Peter Mannon Clinical Gastroenterology and Hepatology Volume 4, Issue 1, Pages (January 2006) DOI: /S (05)00858-X Copyright © 2006 American Gastroenterological Association Terms and Conditions
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Figure 1 Whole mount preparation of normal human platelets (A) and HPS platelets (B) viewed in the transmission electron microscope. Electron-opaque dense bodies are seen as discrete black shapes within the platelets (original magnification 14,000×). Clinical Gastroenterology and Hepatology 2006 4, 73-80DOI: ( /S (05)00858-X) Copyright © 2006 American Gastroenterological Association Terms and Conditions
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Figure 2 Mucosal and histologic findings seen on colonoscopy in 7 HPS patients. (A) Aphthous ulcers (arrows); (B) nodular mucosa (arrow); (C) mucosal erythema; (D) granuloma (arrow); (E) cryptitis (within circle); (F) pigmented macrophages (arrows). Clinical Gastroenterology and Hepatology 2006 4, 73-80DOI: ( /S (05)00858-X) Copyright © 2006 American Gastroenterological Association Terms and Conditions
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