1. Drugging Chromatin in Cancer: Recent Advances and Novel Approaches
Sheng F. Cai, Chun-Wei Chen, Scott A. Armstrong 
Molecular Cell 
Volume 60, Issue 4, Pages (November 2015)
DOI: /j.molcel
Copyright © 2015 Elsevier Inc. Terms and Conditions

2. Figure 1 Strategies for Targeting Epigenetic Regulators
(A) Inhibiting enzymatic activity with competitive small molecule compounds, (B) disrupting protein-protein interactions, and (C) using phthalimide-conjugated small molecules to redirect difficult-to-target proteins for proteasomal degradation via the cereblon (CRBN) E3 ubiquitin (Ub) ligase complex.
Molecular Cell  , DOI: ( /j.molcel )
Copyright © 2015 Elsevier Inc. Terms and Conditions