1. Cardiothoracic Transplantation: Recent Developments
Sally Rushton
Statistics and Clinical Studies
NHS Blood and Transplant
BTS Congress, March 2019

2. Outline Overview of cardiothoracic transplant programmes
Trends in adult heart transplant activity
Trends in adult lung transplant activity
Donor organ utilisation
Patient focussed reporting

3. Outline Overview of cardiothoracic transplant programmes
Trends in adult heart transplant activity
Trends in adult lung transplant activity
Donor organ utilisation
Patient focussed reporting

4. Cardiothoracic Transplant Programmes
Heart
Lung

5. Outline Overview of cardiothoracic transplant programmes
Trends in adult heart transplant activity
Trends in adult lung transplant activity
Donor organ utilisation
Patient focussed reporting

6. Adult heart transplants performed in the UK
72% increase

7. Adult heart transplants - by donor type
Patient survival post-transplant ( )
DBD
DCD
83% survival at
1 year
p=0.95

8. Adult heart transplants - by urgency
Super-urgent scheme
Oct 2016
Median waiting time to transplant (95% CI) DAYS
Super-urgent
9 (6-12)
Urgent
52 (38-66)
Non-urgent
502 ( )

9. Adult heart transplants - by urgency
Super-urgent scheme
Oct 2016
Patient survival post-transplant ( )
Non-urgent
Urgent
Super-urgent
p=0.6
1 year % (95% CI)
85 (76-91)
83 (79-87)
78 (63-88)

10. Outline Overview of cardiothoracic transplant programmes
Trends in adult heart transplant activity
Trends in adult lung transplant activity
Donor organ utilisation
Patient focussed reporting

11. Adult lung transplants performed in the UK
51% increase

12. Adult lung transplants - by transplant type

13. Adult lung transplants - by donor type
Patient survival post-transplant ( )
DBD
DCD
p=0.2
2 years % (95% CI)
73 (69-76)
67 (58-75)

14. Adult lung only transplants - by urgency
Urgent and super-urgent schemes
May 2017
Median waiting time to transplant (95% CI) DAYS
Super-urgent
8 (0-19)
Urgent
23 (14-32)
Non-urgent
531 ( )

15. Adult lung only transplants - by urgency
Patient survival post-transplant (2017/18)
Urgent and super-urgent schemes
May 2017
Non-urgent
Urgent/Super-urgent
p=0.04
12 months % (95% CI)
86 (79-91)
74 (58-84)

16. Outline Overview of cardiothoracic transplant programmes
Trends in adult heart transplant activity
Trends in adult lung transplant activity
Donor organ utilisation
Patient focussed reporting

17. Percentage of DBD organs offered that were transplanted
Heart
Lung N= N=

18. Percentage of “ideal” DBD organs offered that were transplanted
Heart
Lung N= N=
DBDs <56, no past cardiac disease, normal ECG, negative serology,
non-smoker, no history of hypertension or diabetes (CTAG)
DBDs <56, non-smoker, normal x-ray, max pO2>40
(Agence de Biomedecine)

19. Outline Overview of cardiothoracic transplant programmes
Trends in adult heart transplant activity
Trends in adult lung transplant activity
Donor organ utilisation
Patient focussed reporting

20. Infographics
Available on soon

21. Infographics
Available on soon

22. Acknowledgements Members of the Cardiothoracic Advisory Group
Chloe Brown and Rachel Hogg, Statistics and Clinical Studies