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Published byBrynjulf Brynjar Lindberg Modified over 5 years ago
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Steroids Make You Bigger? Fat Chance Says Myc
Akhila Rajan, Norbert Perrimon Cell Metabolism Volume 12, Issue 1, Pages 7-9 (July 2010) DOI: /j.cmet Copyright © 2010 Elsevier Inc. Terms and Conditions
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Figure 1 Ecdysone Signaling Represses dMyc Expression in the Fat Body during the Larval-Pupal Transition to Limit Systemic Growth The prothoracic gland releases ecdysone, which in turn activates the EcR in fat body cells. EcR represses dMyc expression either directly or indirectly. In turn, dMyc has been proposed to upregulate the expression of an unknown humoral signal that activates, either directly or indirectly, IIS in peripheral tissues. Cell Metabolism , 7-9DOI: ( /j.cmet ) Copyright © 2010 Elsevier Inc. Terms and Conditions
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