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Tissue Yield and Diagnostic Efficacy of Fluoroscopic and Cholangioscopic Techniques to Assess Indeterminate Biliary Strictures  Douglas J. Hartman, Adam.

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Presentation on theme: "Tissue Yield and Diagnostic Efficacy of Fluoroscopic and Cholangioscopic Techniques to Assess Indeterminate Biliary Strictures  Douglas J. Hartman, Adam."— Presentation transcript:

1 Tissue Yield and Diagnostic Efficacy of Fluoroscopic and Cholangioscopic Techniques to Assess Indeterminate Biliary Strictures  Douglas J. Hartman, Adam Slivka, Deborah A. Giusto, Alyssa M. Krasinskas  Clinical Gastroenterology and Hepatology  Volume 10, Issue 9, Pages (September 2012) DOI: /j.cgh Copyright © 2012 AGA Institute Terms and Conditions

2 Figure 1 Specimens (A) and patients (B) included in this study.
Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions

3 Figure 2 Representative examples of intraductal biopsies (all H&E stained sections, 100×). (A) Insufficient biopsy composed entirely of blood and fibrin; no tissue or detached epithelial cells are present. (B) An adequate benign bile duct biopsy showing a denuded luminal surface (toward the top of image) and detached epithelial cells (*), as well as a cluster of peribiliary glands within the stromal tissue (arrow). (C) A benign bile duct biopsy showing a denuded luminal surface (toward the top-right of image) and detached epithelial cells (*); even though no peribiliary glands are present, this is an adequate biopsy. (D) A malignant bile duct biopsy showing a partially intact luminal surface with 2 strips of benign surface epithelium (*) and infiltration of the stroma by malignant glands (3 malignant foci are indicated by the arrows); even though no peribiliary glands are present, a diagnosis of malignancy can be rendered. Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions


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