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Orbitofrontal Cortex and Memory Formation

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Presentation on theme: "Orbitofrontal Cortex and Memory Formation"— Presentation transcript:

1 Orbitofrontal Cortex and Memory Formation
Stephen Frey, Michael Petrides  Neuron  Volume 36, Issue 1, Pages (September 2002) DOI: /S (02)

2 Figure 1 Exemplars of the Abstract Color Images that Were Used in the Present PET Experiment The images were displayed one at a time for 4 s in the middle of the monitor. Depending on the condition, participants were asked simply to view or to memorize the material. The participants were tested for memory of the stimuli seen after the completion of the scan. The control condition consisted of three familiar images that were presented randomly, one at a time, to the participants during scanning. Neuron  , DOI: ( /S (02) )

3 Figure 2 Merged PET-MRI Sections Illustrating CBF Activations from the Graded Contrast as Encoding Demands Increased across the Four Encoding Conditions There were two significant peaks in the right orbitofrontal cortical area 11 (y = 55 and y = 34) and one peak in the right orbitofrontal cortical area 25 (y = 12). Significant activation was also present in the right parahippocampal region (y = −38). The location of the different architectonic areas of the human orbitofrontal cortex is indicated according to a recent architectonic study (Petrides and Pandya, 1994) on a 3D diagram of the orbitofrontal cortex (bottom left). IOS, intermediate orbital sulcus; LOS, lateral orbital sulcus; MOS, medial orbital sulcus; OLF, olfactory sulcus; TOS, transverse orbital sulcus. Neuron  , DOI: ( /S (02) )


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