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Severe Hepatic Side Effects of Ezetimibe

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Presentation on theme: "Severe Hepatic Side Effects of Ezetimibe"— Presentation transcript:

1 Severe Hepatic Side Effects of Ezetimibe
Mark F.J. Stolk, Marco C.J.M. Becx, Karel C. Kuypers, Cees A. Seldenrijk  Clinical Gastroenterology and Hepatology  Volume 4, Issue 7, Pages (July 2006) DOI: /j.cgh Copyright © 2006 American Gastroenterological Association Terms and Conditions

2 Figure 1 Laboratory values of patient 1. Week 0 was the time of presentation at the outpatient clinic. alat, alanine aminotransferase; AP, alkaline phosphatase; bili, bilirubin. Clinical Gastroenterology and Hepatology 2006 4, DOI: ( /j.cgh ) Copyright © 2006 American Gastroenterological Association Terms and Conditions

3 Figure 2 Mild mononuclear inflammatory infiltrate with a mild lobular component (H&E stain, magnification 100×). Clinical Gastroenterology and Hepatology 2006 4, DOI: ( /j.cgh ) Copyright © 2006 American Gastroenterological Association Terms and Conditions

4 Figure 3 Laboratory values of patient 2. Ezetimibe was used from weeks 6–19. alat, alanine aminotransferase; AP, alkaline phosphatase; bili, bilirubin. Clinical Gastroenterology and Hepatology 2006 4, DOI: ( /j.cgh ) Copyright © 2006 American Gastroenterological Association Terms and Conditions

5 Figure 4 Extensive chronic inflammatory infiltrate with plasma cells and eosinophils with a strong lobular component; stage 3 fibrosis (A, H&E stain, magnification 200×; B, reticulin stain, magnification 200×). Clinical Gastroenterology and Hepatology 2006 4, DOI: ( /j.cgh ) Copyright © 2006 American Gastroenterological Association Terms and Conditions


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