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An integrated biochemical prediction model of all-cause mortality in patients undergoing lower extremity bypass surgery for advanced peripheral artery.

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Presentation on theme: "An integrated biochemical prediction model of all-cause mortality in patients undergoing lower extremity bypass surgery for advanced peripheral artery."— Presentation transcript:

1 An integrated biochemical prediction model of all-cause mortality in patients undergoing lower extremity bypass surgery for advanced peripheral artery disease  Christopher D. Owens, MD, MS, Ji Min Kim, MPH, Nathanael D. Hevelone, MS, Warren J. Gasper, MD, Michael Belkin, MD, Mark A. Creager, MD, Michael S. Conte, MD  Journal of Vascular Surgery  Volume 56, Issue 3, Pages (September 2012) DOI: /j.jvs Copyright © 2012 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Nelson-Aalen cumulative hazard estimates for death are shown for patients dichotomized by preoperative baseline high-sensitivity C-reactive protein (hsCRP) values higher or lower than 5.0 mg/L. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2012 Society for Vascular Surgery Terms and Conditions

3 Fig 2 A Venn diagram demonstrates the overlap among subsets of patients with malnutrition, renal impairment, and inflammation and shows the synergism of different mechanisms for the hazard ratio (HR) of death. Of 225 patients in this study, 74 (33%) had an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2, 63 (28%) had an albumin concentration of <3.5 mg/dL, and 80 (36%) had high-sensitivity C-reactive protein (hsCRP) concentration of >5.0 mg/L. The 21 patients (9%) located within the intersection of all three circles have an HR for death of 9.08. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2012 Society for Vascular Surgery Terms and Conditions

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