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Do Flies Count Sheep or NMDA Receptors to Go to Sleep?

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Presentation on theme: "Do Flies Count Sheep or NMDA Receptors to Go to Sleep?"— Presentation transcript:

1 Do Flies Count Sheep or NMDA Receptors to Go to Sleep?
Seana Lymer, Justin Blau  Cell  Volume 165, Issue 6, Pages (June 2016) DOI: /j.cell Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 R2 Ring Neurons Function in Drosophila Sleep Homeostasis
Time spent awake and sleep deprivation cause intracellular Ca2+ levels and NMDA receptor abundance to rise in R2 ring neurons in the Drosophila central brain. This increases the number and size of R2 neuron pre-synaptic active zones and R2 firing rates, which promote sleep (top). These changes are plastic: sleep reverses these changes in R2 ring neurons to reduce sleep drive (bottom). Cell  , DOI: ( /j.cell ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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