Presentation is loading. Please wait.

Presentation is loading. Please wait.

Role of TCF4 in signaling crosstalk with NFκB in human chondrocytes

Similar presentations


Presentation on theme: "Role of TCF4 in signaling crosstalk with NFκB in human chondrocytes"— Presentation transcript:

1 Role of TCF4 in signaling crosstalk with NFκB in human chondrocytes
L. Zhong, B. Ma, J.N. Post, M. Karperien  Osteoarthritis and Cartilage  Volume 21, Pages S122-S123 (April 2013) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1 Effects of TCF4/LEF members on MMP mRNA expression: Human primary chondrocytes were infected with adenoviruses expressing GFP, TCF4 and LEF1. MMP mRNA expression was measured by qPCR. Osteoarthritis and Cartilage  , S122-S123DOI: ( /j.joca ) Copyright © Terms and Conditions

3 Figure 2 TCF4 induced NF-kB target gene IL6 mRNA expression by potentiating NF-kB signaling: Human primary chondrocytes were infected with adenoviruses expressing GFP, TCF4 and I kB-a and stimulated with IL1-β. IL-6 mRNA expression was measured by qPCR. Osteoarthritis and Cartilage  , S122-S123DOI: ( /j.joca ) Copyright © Terms and Conditions


Download ppt "Role of TCF4 in signaling crosstalk with NFκB in human chondrocytes"

Similar presentations


Ads by Google