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Recommendations for the management of patients with homozygous familial hypercholesterolaemia: Overview of a new European Atherosclerosis Society consensus.

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Presentation on theme: "Recommendations for the management of patients with homozygous familial hypercholesterolaemia: Overview of a new European Atherosclerosis Society consensus."— Presentation transcript:

1 Recommendations for the management of patients with homozygous familial hypercholesterolaemia: Overview of a new European Atherosclerosis Society consensus statement  Eric Bruckert  Atherosclerosis Supplements  Volume 15, Issue 2, Pages (September 2014) DOI: /j.atherosclerosissup Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 Number of publications on homozygous familial hypercholesterolaemia identified using PubMed in March 2013, shown by year from 2007 to 2012. Atherosclerosis Supplements  , 26-32DOI: ( /j.atherosclerosissup ) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 The heterogeneity of homozygous familial hypercholesterolaemia.
Atherosclerosis Supplements  , 26-32DOI: ( /j.atherosclerosissup ) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

4 Fig. 3 Reduction in low-density lipoprotein cholesterol in patients with homozygous familial hypercholesterolaemia receiving statin therapy alone or in combination with ezetimibe (EZE) [11]. †All patients were receiving statin 40 mg at baseline and prior to switch; *p = 0.02 versus statin only 80 mg; **p < 0.01 versus statin only 80 mg. Atherosclerosis Supplements  , 26-32DOI: ( /j.atherosclerosissup ) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

5 Fig. 4 Estimation of low-density lipoprotein cholesterol (LDL-C) levels achieved upon treatment with current therapies in patients with homozygous familial hypercholesterolaemia, according to the severity of the disease. Atherosclerosis Supplements  , 26-32DOI: ( /j.atherosclerosissup ) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions


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