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Ref.: Textbook of Medical Physiology.

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Presentation on theme: "Ref.: Textbook of Medical Physiology."— Presentation transcript:

1 Ref.: Textbook of Medical Physiology.
13th ed: ,12th. Ed. 11th edition By, Guyton and Hall.

2 Physiology Introduction Cell physiology Membrane physiology
Excitable tissues Nerve Muscle

3 Fig

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5 Fig

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7 NEGATIVE FEEDBACK

8 POSITIVE FEEDBACK

9 Fig

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26 Fig 26

27 Fig 27

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29 Tight Junction

30 Gap Junction

31 Desmosome (Adhering Junction)

32 Transport across Plasma Membranes

33 Transport across Plasma Membranes

34 Transport across Plasma Membranes

35 Diffusion through lipid bilayer
CO2 O2 NO Steroid Hormones Monoglycerides

36 Diffusion through Biological Membranes

37 Simple Diffusion

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39 Fick’s Law J = P.∆C P = D.A/∆X J = D.A.∆C/∆X
J = Flux (Rate of diffusion) P = Permeability D = Diffusion Coefficient A = Surface area C = Concentration X = Membrane thickness

40 Simple Diffusion

41 Simple Diffusion

42 Facilitated Diffusion

43 Facilitated Diffusion

44 Facilitated Diffusion
Aminoacids Glucose Galactose Fructose

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47 Osmosis

48 Osmosis

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50 Osmotic pressure

51 Van’t Hoff’s Law π = RTC π : osmotic Pressure R = Gas constant
T = Absolute Temprature C = Concentration

52 Tonicity of solution 52

53 Hypotonic (cell swells) Isotonic (no change) Hypertonic (cell shrinks)
Figure 25-5; Guyton and Hall 53

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55 Active Transport Mechanisms
Primary active transport Secondary active transport Vesicular transport

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57 Types of Pumps Na+/K+ pump H+ pump H+/K+ pump Ca++ pump

58 Na+ / K+ Pump

59 The importance of pumps for cell functions

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63 Transport is Controlled by
Activation of receptors - Changing activity of certain enzymes

64 Control of Transport

65 Receptors & Enzymes

66 Receptors & Channels

67 Receptors & G proteins

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71 Control of Exocytosis


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