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Closure of the Pericardium Using Synthetic Bioabsorbable Polymers

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Presentation on theme: "Closure of the Pericardium Using Synthetic Bioabsorbable Polymers"— Presentation transcript:

1 Closure of the Pericardium Using Synthetic Bioabsorbable Polymers
Kei Sakuma, MD, Atsushi Iguchi, MD, Yoshito Ikada, MD, Koichi Tabayashi, MD  The Annals of Thoracic Surgery  Volume 80, Issue 5, Pages (November 2005) DOI: /j.athoracsur Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 (A) Group A, autologous pericardium at 2 weeks after implantation. (B) Group B, gelatin sheet at 2 weeks after implantation. (C) Group C, L-lactic acid-ε-caprolactone copolymer at 2 weeks after implantation. (D) Group D, expanded-polytetraflurorethylene sheet at 2 weeks after implantation. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 (A) Group A, autologous pericardium at 4 weeks after implantation. (B) Group B, gelatin sheet at 4 weeks after implantation: no inflammatory reaction was observed. (C) Group C, L-lactic acid-ε-caprolactone copolymer at 4 weeks after implantation: piece of the L-C copolymer formed granulation tissue. (D) Group D, expanded-polytetrafluoroethylene (e-PTFE) sheet at 4 weeks after implantation: neutrophil infiltration is extensive around the e-PTFE seat. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 (A) Group A, autologous pericardium at 12 weeks after implantation. (B) Group B, gelatin sheet at 12 weeks after implantation. (C) Group C, L-lactic acid-ε-caprolactone copolymer at 12 weeks after implantation. (D) Group D, expanded-polytetrafluoroethylene sheet at 12 weeks after implantation. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 (A) Group A, autologous pericardium at 24 weeks after implantation. (B) Group B, gelatin sheet at 24 weeks after implantation: at the site of the remaining gelatin sheet, it has a light inflammatory reaction. (C) Group C, L-lactic acid-ε-caprolactone copolymer at 24 weeks after implantation: the copolymer sheet was almost replaced by a thin layer of fibrous connective tissue with some amount of granulation tissue. (D) Group D, the expanded-polytetrafluoroethylene (e-PTFE) sheet at 24 weeks after implantation: the e-PTFE sheet consisted of dense connective tissue. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Immunostaining findings. In the replaced tissue sections in groups B and C after 24 weeks, a layer of the cells stained for cytokeratin and is likely mesothelium. (Left) Group B, 24 weeks (original magnification, ×200). (Right) Group C, 24 weeks (original magnification, ×200). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2005 The Society of Thoracic Surgeons Terms and Conditions

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