1. (A) Fractional probability of target attainment (expressed as a percentage) of intravenous levofloxacin at 500 mg daily, based on PK in healthy volunteers.
(A) Fractional probability of target attainment (expressed as a percentage) of intravenous levofloxacin at 500 mg daily, based on PK in healthy volunteers. (Generated using data from reference 22.) (B) Fractional probability of target attainment of intravenous levofloxacin at 750 mg daily, based on PK in a clinical efficacy study, compared to MIC distributions of two major nosocomial pneumonia pathogens. (Reprinted from reference 59 with permission. © 2004 by the Infectious Diseases Society of America. All rights reserved.)‏
John Turnidge, and David L. Paterson Clin. Microbiol. Rev. 2007; doi: /CMR