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A Method that Will Captivate U

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1 A Method that Will Captivate U
Sophie Martin, Jeff Coller  Molecular Cell  Volume 59, Issue 5, Pages (September 2015) DOI: /j.molcel Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Chemical Structures of 4-Thiouridine and Uridine Nucleosides
The nucleoside 4-thiouridine (left) can be incorporated into RNA strands instead of uridine (right). The thiol group can then react with disulfide chemistries to lead to biotinylated s4U-RNA, allowing the specific purification of labeled RNA from the cell. Molecular Cell  , DOI: ( /j.molcel ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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