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Published byElsa Eliassen Modified over 5 years ago
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Reducing lipids for CV protection in CKD patients—current evidence
Christoph Wanner, Eberhard Ritz Kidney International Volume 74, Pages S24-S28 (December 2008) DOI: /ki Copyright © 2008 International Society of Nephrology Terms and Conditions
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Figure 1 Triglyceride-enriched very low-density lipoprotein (VLDL) activates nuclear factor-kappa B (NF-κB), which plays a key role in activating a spectrum of pro-inflammatory genes, leading to endothelial dysfunction and oxidative stress. NFκB, nuclear factor κB; IL-6, interleukin 6; COX-2, cyclooxygenase-2; TNF-α, tumor necrosis factor-α; ICAM, intracellular adhesion molecule; VCAM, vascular cell adhesion molecule; ApoCIII, apolipoprotein CIII. Kidney International , S24-S28DOI: ( /ki ) Copyright © 2008 International Society of Nephrology Terms and Conditions
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