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Fig. 5 Local gel scaffold for T cell memory response.

Published byΑἴαξ Παπαστεφάνου Modified over 5 years ago

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Presentation on theme: "Fig. 5 Local gel scaffold for T cell memory response."— Presentation transcript:

1 Fig. 5 Local gel scaffold for T cell memory response.
Local gel scaffold for T cell memory response. (A) Splenocytes isolated from tumor-bearing control and treated mice were analyzed for the presence of CD8+CD44+CD122+ and CD4+CD44+CD122+ central memory T cells (TCM). (B and C) Corresponding quantification of CD4 (B) and CD8 (C) TCM in splenocytes. (D) In vivo bioluminescence imaging of mice after rechallenging with intravenous injection of B16F10 cancer cells. (E) Representative lung photographs (day 10) and (F) H&E staining of lungs collected from control (naïve) and treated (cured) mice after rechallenging. The blue arrowheads indicate metastatic tumors in the lungs. Scale bar, 100 μm. (G) Survival curves for naïve and treated mice. Six mice for each group are shown. Data are means ± SEM. Statistical significance was calculated by one-way ANOVA with Tukey’s post hoc test. **P < 0.01. Chao Wang et al., Sci Transl Med 2018;10:eaan3682 Published by AAAS

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