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Definition and determination of in vitro antibiotic susceptibility breakpoints for bacteria
Jacques Sirot, Patrice Courvalin, Claude-James Soussy Clinical Microbiology and Infection Volume 2, Pages S5-S10 (December 1996) DOI: /j tb00870.x Copyright © 1996 European Society of Clinical Infectious Diseases Terms and Conditions
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Figure 1 Distribution of tetracycline MICs and of corresponding inhibition zone diameters 30-μg disks) for 1000 strains of Staphylococcus aureus. Clinical Microbiology and Infection 1996 2, S5-S10DOI: ( /j tb00870.x) Copyright © 1996 European Society of Clinical Infectious Diseases Terms and Conditions
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Figure 2 Distribution of gentamicin MICs and of corresponding inhibition zone diameters (30-μ disks) for 1000 strains of Klebsiella pneumoniae. Clinical Microbiology and Infection 1996 2, S5-S10DOI: ( /j tb00870.x) Copyright © 1996 European Society of Clinical Infectious Diseases Terms and Conditions
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Figure 3 Distribution of ofloxacin MICs for 850 strains of Enterobacteriaceae: □ nalidixic acid-susceptible strains; ▪, nalidixic acid-resistant strains. Clinical Microbiology and Infection 1996 2, S5-S10DOI: ( /j tb00870.x) Copyright © 1996 European Society of Clinical Infectious Diseases Terms and Conditions
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Figure 4 Correlation between the inhibition zone diameters (mm) obtained with a 5-μg fleroxacin disk (y-axis) and the log2 of the MIC μg/mL) of fleroxacin determined by agar dilution (x-axis) for 649 strains. The least-squaresline of regression (x on y) and thelinear regression coefficient (r) were obtained with a Tektronix computer. Clinical Microbiology and Infection 1996 2, S5-S10DOI: ( /j tb00870.x) Copyright © 1996 European Society of Clinical Infectious Diseases Terms and Conditions
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Figure 5 Dirithromycin. Distribution of 547 clinical isolates belonging to different species in susceptible, intermediate and resistant clinical categories according to MICs (S. I.R.) and inhibition zone diameters (s, i, r) obtained with 15-μg disks. Ss, Ii and Rr denote agreement; Is, Si, Ir and Ri, denote minor discrepancies; Sr and Rs denote major discrepancies. Clinical Microbiology and Infection 1996 2, S5-S10DOI: ( /j tb00870.x) Copyright © 1996 European Society of Clinical Infectious Diseases Terms and Conditions
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