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New hopes for gene therapy

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Presentation on theme: "New hopes for gene therapy"— Presentation transcript:

1 New hopes for gene therapy
Michael Gross  Current Biology  Volume 24, Issue 20, Pages R983-R986 (October 2014) DOI: /j.cub Copyright © Terms and Conditions

2 Human helix: High hopes were placed on the rapid advances in molecular biology, but clinical applications of gene therapy were delayed by early setbacks. (Photo: Courtesy of Genentech.) Current Biology  , R983-R986DOI: ( /j.cub ) Copyright © Terms and Conditions

3 Perfect packaging: A key issue in gene therapy is the choice of the vector used to introduce genetic material into cells. As an alternative to the viruses currently used, polymer nanoparticles have shown some promise. (Image: With permission from from J.C. Sunshine, C.J. Bishop, J.J. Green. (2011). Therapeutic Delivery 2, 493–521.) Current Biology  , R983-R986DOI: ( /j.cub ) Copyright © Terms and Conditions

4 Cool science: Amyotrophic lateral sclerosis (ALS), the neuromuscular disorder made famous by the viral spread of the ice-bucket challenge, is among the neuromuscular disorders that could potentially be treated with gene therapy. (Photo: Gail Teitzel.) Current Biology  , R983-R986DOI: ( /j.cub ) Copyright © Terms and Conditions


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