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Endoscopic Imaging of Angiogenesis In Vivo

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Presentation on theme: "Endoscopic Imaging of Angiogenesis In Vivo"— Presentation transcript:

1 Endoscopic Imaging of Angiogenesis In Vivo
Alexander Meining, Michael B. Wallace  Gastroenterology  Volume 134, Issue 4, Pages (April 2008) DOI: /j.gastro Copyright © 2008 AGA Institute Terms and Conditions

2 Figure 1 NBI-/zoom-Imaging of (A) non-neoplastic mucosa of the esophagus and (B) neoplastic squamous mucosa. Note the expansion and irregularity of the intrapapillary capillary loops (IPCL) of the neoplastic tissue. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

3 Figure 2 Confocal laser scanning imaging of (A) an adenocarcinoma and (B) of normal colonic mucosa. In tumorous tissue, irregular vessels and fluorescein leakage can be demonstrated in contrast to regular vessels surrounding healthy colonic crypts. (C and D) Respective images with intramucosal microvessels enhanced with a specially designed software. In addition to the length, diameter and area of vessels, the percentage of the vessel area in relation to the image as a whole can objectively be documented. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions

4 Figure 3 (A) Confocal laser scanning image of a cholangiocarcinoma at the liver hilus. Malignancy is demonstrated by white streaks resembling enlarged irregular tumor vessels. (B) Corresponding histopathologic image of the tumor after resection with CD-31 immunohistochemistry stain demonstrating an increased number of irregular branching vessels (original magnification, ×400). Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions


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