1. What Is Acute Lung Injury?
Daniel P. Schuster, MD, FCCP 
CHEST 
Volume 107, Issue 6, Pages (June 1995)
DOI: /chest
Copyright © 1995 The American College of Chest Physicians Terms and Conditions

2. Figure 1
Criteria of the American-European Consensus Conference (Conf) for the diagnosis of ALI or ARDS. CXR=chest x-ray; WP=wedge pressure; CHF=congestive heart failure.
CHEST  , DOI: ( /chest )
Copyright © 1995 The American College of Chest Physicians Terms and Conditions

3. Figure 2
Schematic development of hypoxemia (↓ PaO2) and reduced respiratory system compliance (Crs) as a result of acute lung injury. The bold arrows indicate the principal pathway. At each step, however, other processes—directly related, indirectly related, or unrelated—can mimic or exacerbate the changes due to lung injury per se. PMB=vascular permeability; EVLW=extravascular lung water; Pc, Pv, Pw=hydrostatic pulmonary capillary, venous, or wedge pressures, respectively; πc=oncotic pressure; △rPBF=change in regional pulmonary blood flow pattern. “Lymph” refers to lymphatic drainage as well as all other modes of EVLW resolution.
CHEST  , DOI: ( /chest )
Copyright © 1995 The American College of Chest Physicians Terms and Conditions

4. Figure 3
The pulmonary transcapillary escape rate (PTCER), an index of vascular permeability, in a variety of patient groups, as previously reported.7,14,34–36 Note that PTCER is in the same range of values as measured in normal subjects in the following groups of subjects: in smokers without acute illness; clinically inactive interstitial lung disease; in lung allografts (alio) in patients without clinical rejection (Rej) postlung transplantation (LT). PTCER is not significantly different from normal in patients with congestive heart failure (CHF). It is highest in patients with ARDS and in lung regions with lobar pneumonia. Other patient populations have intermediate values.
CHEST  , DOI: ( /chest )
Copyright © 1995 The American College of Chest Physicians Terms and Conditions

5. Figure 4
Reported mortalities for ARDS in the following studies: 1 is reference 28; 2 is reference 37; 3 is reference 19; 4 is reference 20; 5 is reference 22; 6 is reference 27; 7 is reference 25; 8 is reference 26; 9 is reference 23; 10 is reference 18; 11 is reference 17; 12 is reference 21; 13 is reference 29; 14 is reference 24.
CHEST  , DOI: ( /chest )
Copyright © 1995 The American College of Chest Physicians Terms and Conditions