1. The neuropathology of brain metastases
Mark Fabian, Mark Walker 
Diagnostic Histopathology 
Volume 25, Issue 1, Pages 1-7 (January 2019)
DOI: /j.mpdhp
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2. Figure 1
A case of metastatic melanoma showing a well-defined border with adjacent brain parenchyma and prominent pigment production (H&E, 2×).
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3. Figure 2
A case of glioblastoma showing infiltrative spread into surrounding brain parenchyma (H&E, 2×).
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4. Figure 3
Metastatic melanoma showing a diffuse pattern of infiltration with single cells and small clusters (H&E, 5×).
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5. Figure 4
Growth of metastatic lung adenocarcinoma within the subarachnoid space of the cerebellum, with extension of tumour into the parenchyma via the perivascular space (H&E, 5×).
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6. Figure 5
A case of olfactory neuroblastoma (Hyams grade 2) showing tumour impinging on the inferior frontal lobe through direct invasion of the cribriform plate (H&E, 10×).
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7. Figure 6
CSF cytospin preparation showing leptomeningeal involvement by metastatic breast carcinoma. There is marked cytological atypia with occasional intracytoplasmic vacuoles and binucleate forms (Diff-Quik, 40×).
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8. Figure 7
Immunocytochemical staining with MNF116 in the case of metastatic breast carcinoma shown in Figure 4 (MNF116, 40×).
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9. Figure 8
Epithelioid glioblastoma showing a relatively well-defined border with adjacent brain parenchyma (H&E, 4×).
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10. Figure 9
Higher magnification view of the case shown in Figure 7, showing the prominent epithelioid morphology with well-defined cell borders and relative lack of cytoplasmic processes. (H&E, 20×).
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11. Figure 10
Anaplastic meningioma showing poor differentiation with cellular pleomorphism, prominent nucleoli and a high mitotic rate. Cellular whorl formation on the superficial aspect helps reveal this tumour's meningothelial origin (H&E, 10×).
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12. Figure 11
A highly cellular CSF specimen showing florid reactive changes associated with chronic inflammation (Diff-Quik, 40×).
Diagnostic Histopathology  , 1-7DOI: ( /j.mpdhp )
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