1. Major differences in inflammatory dendritic cells and their products distinguish atopic dermatitis from psoriasis 
Emma Guttman-Yassky, MD, MSc, Michelle A. Lowes, MBBS, PhD, Judilyn Fuentes-Duculan, MD, Julia Whynot, BSc, Inna Novitskaya, MSc, Irma Cardinale, MSc, Asifa Haider, PhD, Artemis Khatcherian, MSc, John A. Carucci, MD, PhD, Reuven Bergman, MD, James G. Krueger, MD, PhD 
Journal of Allergy and Clinical Immunology 
Volume 119, Issue 5, Pages (May 2007)
DOI: /j.jaci
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
Quantification of the cellular microenvironment in normal skin, psoriasis, and AD. Cell counts/mm and means in normal epidermis (N epi), normal dermis (N derm), psoriatic epidermis (P epi), psoriatic dermis (P derm), AD epidermis (AD epi), and AD dermis (AD derm). ∗P < .05, ∗∗P < .01, ∗∗∗P < .001.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Fig 2
Double-label immunofluorescence confirmed the dermal presence of CD1a+ cells in AD and the lack of complete overlap with langerin, in contrast with normal skin. A and B, Normal skin; C-F, AD. CD11c and CD1a were not coexpressed (A), whereas langerin and CD1a+ were nearly completely coexpressed (B) in normal skin. In AD, there was only partial coexpression of CD1a+ and langerin, with substantial dermal localization of CD1a+ cells (C), and partial coexpression of CD11c+ and CD1a+ cells (D) in both epidermis and dermis. In AD, CD11c+ cells colocalized with FcɛRI and CD206 markers in the upper dermis (E and F).
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4. Fig 3
Genomic expression differences in AD compared to psoriasis. A, RT-PCR analysis of selected genes in AD, lesional psoriasis (LS PS), nonlesional psoriasis (NL PS), and normal skin. Mean gene expression values/hARP are shown (SEM), with statistical analyses indicated. B and C, Heat maps showing the differences in expression of proinflammatory DC products between AD and psoriasis, upregulated genes in AD (B), and psoriasis (C). FC and P values represent AD versus psoriasis.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5. Fig 4
A proposed alternate model of dermal DC plasticity during cutaneous inflammation. Depending on environmental triggers, as well as intrinsic or genetic differences, dermal CD11c+ DCs differentiate to an inflammatory DC. These IDEC-like interstitial DCs encompass both the proposed atopic DC in AD and TIP-DC in psoriasis.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions