1. Association between Genetic Variants in the Base Excision Repair Pathway and Outcomes after Hematopoietic Cell Transplantations 
Bharat Thyagarajan, Bruce Lindgren, Saonli Basu, Sriharsha Nagaraj, Myron D. Gross, Daniel J. Weisdorf, Mukta Arora 
Biology of Blood and Marrow Transplantation 
Volume 16, Issue 8, Pages (August 2010)
DOI: /j.bbmt
Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions

2. Figure 1
Cumulative incidence estimates for treatment-related mortality (TRM) according to different categories of SNP score (P < .001). Disease relapse was used as the competing risk in this model. The SNPs rs167715, rs , and rs were used to create the SNP score variable. Each individual received 1 point for each allele associated with increased incidence of TRM (ie, “deleterious alleles”). Because the mutant alleles for SNPs rs (A allele) and rs (A allele) were associated with increased TRM risk, individuals received 0 points for being homozygous for the wild-type allele (ie, G/G genotype), 1 point for being heterozygous (ie, G/A genotype), and 2 points for being homozygous for the mutant allele (ie, A/A genotype) for each of these SNPs. Because the mutant allele for rs was associated with decreased TRM risk, individuals received 2 points if they had the normal genotype (ie, T/T genotype), 1 point for being heterozygous (ie, T/C genotype), and 0 points for being homozygous for the mutant allele for rs (ie, C/C genotype).
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt )
Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions

3. Figure 2
Cumulative incidence estimates for disease relapse according to rs (P = .007). Treatment-related mortality was used as the competing risk in this model.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt )
Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions