1. The Science of “PMSing”
Progesterone & Estrogen
Chandana & Pranita

2. About Progesterone Secreted by the corpus luteum Steroid
Target tissue- the uterus
Maintains the uterine lining built by estrogen
Prepares mammary glands for secretory functions
Prepares and maintains uterus for embryo if egg is fertilized
In the event that the egg is fertilized, it signals the lining to stimulate the growth of blood vessels to nourish the embryo

3. Controlling Progesterone

4. Progesterone’s Role in Homeostasis
Progesterone has bone forming activity
Binds to receptors on osteoblasts to signal bone forming activity
Maintains lining
Regulates pregnancy

5. Consequences of hyper and hypo secretion
Too little:
- If pregnant, can lead to miscarriage
-Irregular and heavy menustrations
-anxiety
-PMS
Too much:
- fatigue
-dizziness
-water retention
-depression

6. Estrogen Estrone,Estradiol,Estriol Steroid Hormone
Multiple target tissues (Bones,Liver)
Estrogen is required to form the ovum during oogenesis
Prepares uterus for ovum
Released by the ovaries,placenta,corpus luteum

7. Maintaining Homeostasis
Energy Expenditure
Adipose tissue distribution
Food intake
Regulates body development
Menstrual Cycle in women

8. Consequences of Hypo & Hyper Secretion
worsen pre-existing ovarian or breast cancers
Ovulation decreases or stops all together
Hypo -
Obesity
Mood Swings
affects absorption and utilization of calcium and vitamin D (Osteoporosis)
Fetal Demise (in Pregnant women)
Congenital Adrenal Hypoplasia
Type 2 Diabetes
Heart Attacks

9. Analogy
Think of Bruce Banner (the Hulk) as Progesterone and Tony Stark (Iron man) as Estrogen...

10. The partnership between the HULK & Tony Stark.

11. Bibliography for Progesterone
Burch, Candace. "Know Your Hormones." Your Hormone Balance. 10 Feb <
"NW Integrative Medicine." Signs of Hormone Imbalance. 11 Feb <
"Progesterone | Progestin | HealthyWomen." Progesterone | Progestin | HealthyWomen. 10 Feb <
"Progesterone (hormone)." Encyclopedia Britannica Online. Encyclopedia Britannica. 10 Feb <
"You & Your Hormones." You & Your Hormones. Jan Feb <
"The Effects of Hormones on Mood." The Effects of Hormones on Mood. 11 Feb. 2014
Bibliography for Estrogen
"Endocrine System Information." Endocrine System Information. N.p., n.d. Web. 10 Feb <
"Hormones of the Reproductive System." Hormones of the Reproductive System. N.p., n.d. Web. 10 Feb <
"e.hormone | The Hormones : Estrogens." e.hormone | The Hormones : Estrogens. N.p., n.d. Web. 11 Feb <
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