1. Volume 147, Issue 6, Pages 1255-1266.e21 (December 2014)
Development and Validation of a Symptom-Based Activity Index for Adults With Eosinophilic Esophagitis 
Alain M. Schoepfer, Alex Straumann, Radoslaw Panczak, Michael Coslovsky, Claudia E. Kuehni, Elisabeth Maurer, Nadine A. Haas, Yvonne Romero, Ikuo Hirano, Jeffrey A. Alexander, Nirmala Gonsalves, Glenn T. Furuta, Evan S. Dellon, John Leung, Margaret H. Collins, Christian Bussmann, Peter Netzer, Sandeep K. Gupta, Seema S. Aceves, Mirna Chehade, Fouad J. Moawad, Felicity T. Enders, Kathleen J. Yost, Tiffany H. Taft, Emily Kern, Marcel Zwahlen, Ekaterina Safroneeva 
Gastroenterology 
Volume 147, Issue 6, Pages e21 (December 2014)
DOI: /j.gastro
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2. Figure 1
Conceptual framework for the development of EEsAI instruments. The EndoFlip or mucosal biomarkers, were not, as of yet, evaluated for the purposes of the EEsAI study. EndoFlip, Endolumenal Functional Lumen Imaging Probe.
Gastroenterology  , e21DOI: ( /j.gastro )
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3. Figure 2
Box plots of patient-assessed EoE severity distribution by endoscopic/histologic activity. The box contains the 25th–75th percentiles of values, the horizontal line in the middle of the box represents the median. Eos, eosinophils.
Gastroenterology  , e21DOI: ( /j.gastro )
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4. Figure 3
(A) The correlation plot between the EEsAI PRO score and the PatGA in the validation group. (B) The Bland–Altman plot for the agreement between the EEsAI PRO score and the PatGA in the validation group. The grey box indicates the 95% limits of agreement.
Gastroenterology  , e21DOI: ( /j.gastro )
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5. Supplementary Figure 1 Timetable for the adult EEsAI study.
Gastroenterology  , e21DOI: ( /j.gastro )
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6. Supplementary Figure 2 Patient input.
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7. Supplementary Figure 3
Extract of the survey to gain patient input on EoE-related symptoms.
Gastroenterology  , e21DOI: ( /j.gastro )
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8. Supplementary Figure 4 Conceptual model of the study.
Gastroenterology  , e21DOI: ( /j.gastro )
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9. Supplementary Figure 5 Key domains of EoE-related symptoms.
Gastroenterology  , e21DOI: ( /j.gastro )
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10. Supplementary Figure 6
The relationship between the PatGA of EoE severity and the PRO components that were chosen for the construction of the PRO score. The data for the 7-day recall period are shown. TS, trouble swallowing.
Gastroenterology  , e21DOI: ( /j.gastro )
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