1. Gas Chromatography/Mass Spectrometry Characterization of Corticosteroid Metabolism in Human Immortalized Keratinocytes 
Andrzej Slominski 
Journal of Investigative Dermatology 
Volume 118, Issue 2, Pages (February 2002)
DOI: /j x x
Copyright © 2002 The Society for Investigative Dermatology, Inc Terms and Conditions

2. Figure 1
PROG and DOC metabolism. TLC separation of products of PROG (P4) and DOC metabolism in cultured human keratinocytes was done using the following solvents: methanol 6%/chloroform/water 0.01% (MEOH: CHL); acetone 20%/chloroform (ACETONE: CHL); and tetrahydrofuran 50%/chloroform (THF:CHL).
Journal of Investigative Dermatology  , DOI: ( /j x x)
Copyright © 2002 The Society for Investigative Dermatology, Inc Terms and Conditions

3. Figure 2
Mass spectra of the MOTMS derivatives of the steroids identified as (A) 3α,21-dihydroxy-5α-pregnan-20-one (3α,5α-THDOC) and (B) 3α,6,21-trihydroxy-5α-pregnan-20-one (6-hydroxyTHDOC). Insert: predicted structure of the compound.
Journal of Investigative Dermatology  , DOI: ( /j x x)
Copyright © 2002 The Society for Investigative Dermatology, Inc Terms and Conditions

4. Figure 3
Mass spectra of the MOTMS derivatives of the steroids identified as (A) 3 β,21-dihydroxy-5-pregnen-20-one (3 βΔ5-21-OHpregnenolone), (B) 3α,21-dihydroxy-5-pregnen-20-one (3αΔ5-21-OHpregnenolone), and (C) standard (authentic) 3β,21-dihydroxy-5-pregnen-20-one. Insert: predicted structure of the compound.
Journal of Investigative Dermatology  , DOI: ( /j x x)
Copyright © 2002 The Society for Investigative Dermatology, Inc Terms and Conditions

5. Figure 4
Proposed pathway for the metabolism of DOC in human keratinocytes.
Journal of Investigative Dermatology  , DOI: ( /j x x)
Copyright © 2002 The Society for Investigative Dermatology, Inc Terms and Conditions