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Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation  Jacques Donnez,

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Presentation on theme: "Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation  Jacques Donnez,"— Presentation transcript:

1 Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation  Jacques Donnez, M.D., Ph.D., Marie-Madeleine Dolmans, M.D., Ph.D., Antonio Pellicer, M.D., Ph.D., Cesar Diaz-Garcia, M.D., Maria Sanchez Serrano, M.D., Kristen Tryde Schmidt, M.D., Ph.D., Erik Ernst, M.D., Ph.D., Valérie Luyckx, M.D., Claus Yding Andersen, M.Sc., D.M.Sc.  Fertility and Sterility  Volume 99, Issue 6, Pages (May 2013) DOI: /j.fertnstert Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Ovarian cortex reimplantation on the ovarian medulla. Large pieces of thawed ovarian cortex are sutured to the medulla. From Donnez et al., 2006 (1). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Ovarian cortex reimplantation in a peritoneal pocket. Large pieces of ovarian cortex are placed in a peritoneal pocket. From Donnez et al., 2012 (31). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

4 Figure 3 Ovarian cortical biopsy demonstrating the distance between the mesothelium and primordial follicles, ranging from 414 μm to 617 μm. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

5 Figure 4 Impact of grafting on the resting follicle pool: potential influence of c-Kit/Kit ligand (KL), hypoxia, and antimüllerian hormone (AMH). From David et al. (65). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

6 Figure 5 Fertility preservation methods in women at risk of POF depending on patient age and possible delay before starting chemotherapy. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions


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