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In vitro fertilization and pregnancy rates: the influence of sperm motility and morphology on IVF outcome  Eilish T. Donnelly, Ph.D., Sheena E.M. Lewis,

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Presentation on theme: "In vitro fertilization and pregnancy rates: the influence of sperm motility and morphology on IVF outcome  Eilish T. Donnelly, Ph.D., Sheena E.M. Lewis,"— Presentation transcript:

1 In vitro fertilization and pregnancy rates: the influence of sperm motility and morphology on IVF outcome  Eilish T. Donnelly, Ph.D., Sheena E.M. Lewis, Ph.D., James A. McNally, B.Sc., William Thompson  Fertility and Sterility  Volume 70, Issue 2, Pages (August 1998) DOI: /S (98)

2 FIGURE 1 Differences in progressive motilities of neat and prepared sperm samples that (A) achieved ≥50% or <50% fertilization in vitro and (B) achieved pregnancy and those that did not. Values are medians (□) interquartile ranges (□ 25%–75%). ∗Significantly lower than samples that achieved ≥50% fertilization (P < .005). †Significantly lower than samples that achieved pregnancy (P ≤ .01). ‡Significantly lower than samples that achieved pregnancy (P ≤ .005; Mann-Whitney U test). Fertility and Sterility  , DOI: ( /S (98) )

3 FIGURE 2 Differences in average path velocities of neat and prepared sperm samples that (A) achieved ≥50% or >50% fertilization in vitro and (B) achieved pregnancy and those that did not. Values are medians (□) with interquartile ranges (□ 25%–75%). ∗Significantly lower than samples that achieved ≥50% fertilization (P ≤ .05). †Significantly lower than samples that achieved ≥50% fertilization (P ≤ .01). ‡Significantly lower than samples that achieved ≥50% fertilization (P ≤ .005). §Significantly lower than samples that achieved pregnancy (P ≤ .01. ∥Significantly lower than samples that achieved pregnancy (P ≤ .005, Mann-Whitney U test). Fertility and Sterility  , DOI: ( /S (98) )

4 FIGURE 3 Differences in straightness of neat and prepared sperm samples that (A) achieved ≥50% or <50% fertilization in vitro and (B) achieved pregnancy and those that did not. Values are medians (□) with interquartile ranges (□ 25%–75%). ∗Significantly lower than samples that achieved ≥50% fertilization (P ≤ .05). †Significantly lower than samples that achieved pregnancy (P ≤ .05). ‡Significantly lower than samples that achieved pregnancy (P ≤ .01; Mann-Whitney U test). Fertility and Sterility  , DOI: ( /S (98) )

5 FIGURE 4 Differences in percentage hyperactivation of neat and prepared sperm samples that (A) achieved ≥50% or <50% fertilization in vitro and (B) achieved pregnancy and those that did not. Values are medians (□) with interquartile ranges (□ 25%–75%). ∗Significantly lower than samples that achieved ≥50% fertilization (P ≤ .005). †Significantly lower than samples that achieved pregnancy (P ≤ .01; Mann-Whitney U test). Fertility and Sterility  , DOI: ( /S (98) )

6 FIGURE 5 Differences in percentage normal morphologies of neat and prepared sperm samples that (A) achieved ≤50% or <50% fertilization in vitro and (B) achieved pregnancy and those that did not. Values are medians (□) with interquartile ranges (□ 25%–75%). ∗Significantly lower than samples that achieved ≥50% fertilization (P ≤ .005). †Significantly lower than samples that achieved pregnancy (P ≤ .01; Mann-Whitney U test). Fertility and Sterility  , DOI: ( /S (98) )


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