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iRhoms: A Potential Path to More Specific Therapeutic Targeting of Lupus Nephritis
Andreas Herrlich, Eirini Kefaloyianni American Journal of Kidney Diseases Volume 72, Issue 4, Pages (October 2018) DOI: /j.ajkd Copyright © 2018 National Kidney Foundation, Inc. Terms and Conditions
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Figure 1 Effects of iRhom2 knockout on lupus nephritis. iRhom2 acts downstream of the initial glomerular damage by immunecomplex deposition in LN. Some of its roles can be mimicked with inhibition of EGFR or TNFα. American Journal of Kidney Diseases , DOI: ( /j.ajkd ) Copyright © 2018 National Kidney Foundation, Inc. Terms and Conditions
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