1. Induced pluripotent stem cells: From Nobel Prizes to clinical applications 
S. Tamir Rashid, Graeme J.M. Alexander 
Journal of Hepatology 
Volume 58, Issue 3, Pages (March 2013)
DOI: /j.jhep
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

2. Fig. 1
Derivation of pluripotent stem cells. Pluripotent stem cells, possessing the ability to form any cell type of the human body, can be created using in vitro fertilisation (Steptoe and Edwards), somatic cell nuclear transfer (Gurdon), and transcription factor overexpression (Yamanaka).
Journal of Hepatology  , DOI: ( /j.jhep )
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions

3. Fig. 2
Using iPSCs for human therapy. Patient specific skin samples are firstly reprogrammed into iPSCs. Genetic diseases could then be treated by editing the genomes of iPSCS, differentiating them into target adult cells, and finally transplanting the corrected cells back into the original patient.
Journal of Hepatology  , DOI: ( /j.jhep )
Copyright © 2012 European Association for the Study of the Liver Terms and Conditions