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A. Dyson, S. Cone, M. Singer, G.L. Ackland 

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1 Microvascular and macrovascular flow are uncoupled in early polymicrobial sepsis 
A. Dyson, S. Cone, M. Singer, G.L. Ackland  British Journal of Anaesthesia  Volume 108, Issue 6, Pages (June 2012) DOI: /bja/aes093 Copyright © 2012 The Author(s) Terms and Conditions

2 Fig 1 Macrovascular phenotype in naive, sham-operated, and septic rats. (a) Mean arterial pressure. (b) Heart rate. (c) Stroke volume. (d) Cardiac output. All data (measured at 6 h post-surgery) are displayed as median (IQR). *Difference (P<0.01; the Kruskal–Wallis test) between severe sepsis and other conditions; #Differences (P<0.01; the Kruskal–Wallis test) between naive and mild septic rats. British Journal of Anaesthesia  , DOI: ( /bja/aes093) Copyright © 2012 The Author(s) Terms and Conditions

3 Fig 2 Microvascular phenotype in naive, sham-operated, and septic rats, measured at 6 h post-surgery. (a) Raw MFI scores in relation to stroke volume (R2=0.13; P=0.08; Spearman’s rank correlation test). (b) Microvascular flow heterogeneity index. (c) Perfused small-vessel density. (d) The De Backer score. Data displayed as (a) raw data, (b–d) [median (IQR)]. *Difference (P<0.05, the Kruskal–Wallis test) between naive and other treatment groups. British Journal of Anaesthesia  , DOI: ( /bja/aes093) Copyright © 2012 The Author(s) Terms and Conditions


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