1. Reprint of: B Cells in Chronic Graft-versus-Host Disease
Stefanie Sarantopoulos, Bruce R. Blazar, Corey Cutler, Jerome Ritz 
Biology of Blood and Marrow Transplantation 
Volume 21, Issue 2, Pages S11-S18 (February 2015)
DOI: /j.bbmt
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2. Figure 1
BAFF and antigen-driven B cell activation. In cGVHD, B cells are promoted by antigen and excessive BAFF levels to survive and produce antibodies. Constitutive antibody production by certain B cell subsets in cGVHD may directly mediate pathology. B cells may also serve as antigen presenting cells (APC).
Biology of Blood and Marrow Transplantation  , S11-S18DOI: ( /j.bbmt )
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3. Figure 2
Development and persistence of potentially pathological cGVHD B cells. Altered B cell homeostasis with high BAFF to naïve B cell ratios after HCT leads to persistence of aberrantly activated B cells. Decreased bone marrow output and production of immature (and potentially of B10) B cells leads to excessive levels of BAFF, sufficient to support potentially pathological B cell subsets.
Biology of Blood and Marrow Transplantation  , S11-S18DOI: ( /j.bbmt )
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