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Refinement of the Locus for Autosomal Recessive Retinitis Pigmentosa (RP25) Linked to Chromosome 6q in a Family of Pakistani Origin  Shagufta Khaliq,

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Presentation on theme: "Refinement of the Locus for Autosomal Recessive Retinitis Pigmentosa (RP25) Linked to Chromosome 6q in a Family of Pakistani Origin  Shagufta Khaliq,"— Presentation transcript:

1 Refinement of the Locus for Autosomal Recessive Retinitis Pigmentosa (RP25) Linked to Chromosome 6q in a Family of Pakistani Origin  Shagufta Khaliq, Abdul Hameed, Muhammed Ismail, S. Qasim Mehdi, David A.R. Bessant, Annette M. Payne, Shomi S. Bhattacharya  The American Journal of Human Genetics  Volume 65, Issue 2, Pages (August 1999) DOI: /302493 Copyright © 1999 The American Society of Human Genetics Terms and Conditions

2 Figure 1 Family pedigree and haplotypes in the disease region of 6q. For each individual, the disease haplotype is shown as a blackened bar. The American Journal of Human Genetics  , DOI: ( /302493) Copyright © 1999 The American Society of Human Genetics Terms and Conditions

3 Figure 2 Boundaries of the chromosomal interval containing the 6q arRP gene, in relation to the critical intervals for other eye disorders mapping to this region. Our results indicate either that GABA-receptor candidate genes are no longer candidates for this phenotype or that there are in fact two arRP loci in close proximity on 6q. The American Journal of Human Genetics  , DOI: ( /302493) Copyright © 1999 The American Society of Human Genetics Terms and Conditions


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