1. a) Low magnification histopathological biopsy showing typical features of usual interstitial pneumonia pattern with a heterogeneous appearance and areas of fibrosis with scarring and honeycomb change.
a) Low magnification histopathological biopsy showing typical features of usual interstitial pneumonia pattern with a heterogeneous appearance and areas of fibrosis with scarring and honeycomb change. Areas with less affected parenchyma also show emphysematous changes. b) Higher magnification of the histopathological biopsy reveals diffuse pulmonary involvement of numerous macrophage accumulations within most of the distal airspaces, consistent with a desquamative interstitial pneumonia pattern. Image courtesy of Philipp A. Schnabel (Institute of Pathology, University of Heidelberg, Heidelberg, Germany).
Michael Kreuter et al. Eur Respir Rev 2014;23:
©2014 by European Respiratory Society