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The Work of Gregor Mendel 11-1
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Transmission of characteristics from _______________________is called ___________________.
The _________ that studies _____ those characteristics are _________ from one generation to the next is called ___________________ parents to offspring heredity how SCIENCE passed on Genetics
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Gregor Mendel The __________________ is _________________,
The __________________ is _________________, a monk whose _________ of genetic traits was the beginning of our _________________ about _____________________. Father of Genetics Gregor Mendel study understanding how genes work
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_______ part of flower makes ___________ (sperm)
Mendel designed ____________ using __________ in the monastery garden _______ part of flower makes ___________ (sperm) __________ part of flower makes _______ cells experiments Pea plants MALE Pollen FEMALE egg
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In pea plants, the pollen normally joins with an egg from the _______ plant (=_______________ ) so seeds have “_________________” same Self pollinating ONE parent
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MENDEL’S PEA EXPERIMENTS
Mendel started his experiments with peas that were _________________ = if allowed to _________________ they would produce ____________________ to themselves. true breeding self pollinate offspring identical
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A _____________________ is called a ____________
Mendel ______________ in peas. specific characteristic trait studied 7 traits Pearson Education Inc,; Publishing as Pearson Prentice Hall
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MENDEL’S PEA EXPERIMENTS
removed pollen Mendel ____________________ making parts and ____________ from _______ plant. This allowed him to _____________ plants with ______________ characteristics and ________ the results added pollen another cross-breed different study
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____ generation (_________) ____ generation (______= offspring)
MENDEL’S EXPERIMENTS P1 ____ generation (_________) ____ generation (______= offspring) ___ generation parental F1 filial F2
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Principles of Dominance
Section 11-1 P Generation F1 Generation F2 Generation Tall Short Tall Tall Tall Tall Tall Short
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Principles of Dominance
Section 11-1 P Generation F1 Generation F2 Generation Tall Short Tall Tall Tall Tall Tall Short
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Principles of Dominance
Section 11-1 P Generation F1 Generation F2 Generation Tall Short Tall Tall Tall Tall Tall Short
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crossed PURE When Mendel ______________ PLANTS with 2 ______________ traits: (EX: Tall crossed with short) He always found same pattern: 1. ONLY ______ trait ____________ in the ____ generation BUT . . . 2. ___________ trait ____________ in the ____ generation in a _________ ratio contrasting ONE showed F1 Missing returned F2 3:1
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PATTERNS ARE THE KEY Image modified from:
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__________ must be able to _______ the other. pair of FACTORS control
Mendel decided that there must be a __________________ that ________each trait and that __________ must be able to _______ the other. pair of FACTORS control one factor HIDE
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We now know that Mendel’s ________________ carried on
the pair of________________ _________________ factors are genes homologous chromosomes
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trait are called ___________.
________ gene _______ for a trait are called ___________. DIFFERENT CHOICES ALLELES
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DOMINANT HIDES RECESSIVE is hidden by
__________________ = An allele that ________ the presence of another allele __________________ = An allele that __________________ the presence of another allele HIDES RECESSIVE is hidden by
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Dominant Recessive No Hitchhikers thumb Hitchhikers thumb
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Dominant Recessive Dwarfism Norman Growth
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The pattern corresponds to the ____________ of ______________ during
Why did the recessive trait disappear in the F1 generation and reappear in the F2? The pattern corresponds to the ____________ of ______________ during ____________________ movement chromosomes MEIOSIS Image modified from:
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WHAT DOES MEIOSIS HAVE TO DO WITH IT?
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REMEMBER SEGREGATION _____________ chromosomes ________________ during
ANAPHASE I = _________________ HOMOLOGOUS SEPARATE SEGREGATION Image modified from:
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F1 received carrying shortness
____ offspring __________ an allele for tallness from their _______ parent and an allele for shortness from their ________ parent. The F1 plants ALL ___________ but are ___________ an allele for _____________ F received TALL SHORT LOOK TALL carrying shortness Images from: BIOLOGY by Miller & Levine; Prentice Hall Publishing ©2006
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made gametes reappears EXPLAINING the F1 CROSS
LAW OF ___________________ SEGREGATION alleles are separated when the F1 plants ______________ When these gametes recombined to make the F2 generation, the _____________ trait _______________ in ¼ of the offspring made gametes recessive reappears Image from: BIOLOGY by Miller & Levine; Prentice Hall Publishing ©2006
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DOMINANT/RECESSIVE T t capital Dominant Recessive lower-case
_____________ allele is represented by a ____________ letter. (usually the first letter of the trait) ____________ allele is represented by the SAME _________________ letter. EX: Tall = ______ Short =______ capital Recessive lower-case T t NOT S for short
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HOMOZYGOUS HETEROZYGOUS
When both alleles in the pair are the _______, the organism is _______________ or __________ EX: ____ or ___ When both alleles in the pair are _____________, the organism is _________________ or _____________ Ex: ____ SAME HOMOZYGOUS PURE TT tt DIFFERENT HETEROZYGOUS HYBRID Tt
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PHENOTYPE/GENOTYPE The ________________ of an organism is its _____________ The ____________of an organism is its _____________ genetic makeup GENOTYPE appearance PHENOTYPE
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MAKING A CROSS for only a __________ trait = ____________________
ONE GENE MONOHYBRID CROSS A Punnett square for a MONOHYBRID CROSS looks like this:
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PUNNETT SQUARES are used to show possible offspring from a cross between 2 parents _______________ go at top and on left side Boxes show ____________ ___________________ Parent alleles T T T t possible offspring combinations
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STEPS FOR MAKING CROSSES
Figure out parent alleles Choose Punnett size Put in parent gametes Fill in offspring combinations probabilities phenotypes genotypes 1. ___________ what _________________ are 2. ________correct__________ square __________ 3. ______ possible_______________________ 4. ______ boxes with _____________________ 5. Determine ____________of_____________& ____________
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T t TALL = ____ SHORT = ____ IN PEA PLANTS Tall is dominant over short
LET’S MAKE A CROSS! PURE TALL PURE SHORT X
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PURE TALL parent What are the parent alleles?
T T _________ HOMOZYGOUS What gametes can it make? T T
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PURE SHORT parent What are the parent alleles?
t t _________ HOMOZYGOUS What gametes can it make? t t
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T t T t T t T t T t ALL _____ of the offspring ____ % ___/4 will be
100 4 T t T t Tt TALL GENOTYPE _____ PHENOTYPE _______
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HYBRID TALL parent What are the parent alleles?
T t _________ HETEROZYGOUS What gametes can it make? T t
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T t T t T t T T T t t t GENOTYPES ¼ = _____ ½ = _____ TT Tt tt 3/4 75
TALL PHENOTYPES ____ or ____% _________ ____ or ____% _________ 1/4 25 SHORT
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PRACTICE MAKING GAMETES for a MONOHYBRID CROSS
Tall = ____ Round seeds = ___ Short = ____ Wrinkled seeds = ___ T t r
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What are the possible gametes?
Homozygous Tall parent = What gametes can it produce? T T T T
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What are the possible gametes?
PURE wrinkled parent = What gametes can it produce? rr r r
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What are the possible gametes?
Heterozygous Round parent = What gametes can it produce? R r R r
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What are the possible gametes?
Hybrid Tall parent = What gametes can it produce? Tt T t
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Section 10.2 Read section 10.2 to review making monohybrid crosses
Complete Practice 1and practice 2
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O T T F F S S E __ What comes next?
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It’s EASY if you know the PATTERN! (Just like Punnett Squares)
9 NINE O T T F F S S E __ I V E X EVEN IGHT N E W O H R E O U R
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PROBABILITY & PUNNETT SQUARES 11-2
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Tossing Coins If you toss a coin, what is the probability of getting heads? Tails? If you toss a coin 10 times, how many heads and how many tails would you expect to get? Working with a partner, have one person toss a coin 10 times, tally the number of times you get heads/tails then switch
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Results will vary, but should be close to 5 heads and 5 tails.
Assuming that you expect 5 heads and 5 tails in 10 tosses, how do the results of your tosses compare? How about the results of your partner’s tosses? How close was each set of results to what was expected? Add your results to those of your partner to produce a total of 20 tosses. Assuming that you expect 10 heads and 10 tails in 20 tosses, how close are these results to what was expected? If you compiled the results for the whole class, what results would you expect? How do the expected results differ from the observed results? Results will vary, but should be close to 5 heads and 5 tails. The results for 20 tosses may be closer to the predicted 10 heads and 10 tails. The results for the entire class should be even closer to the number predicted by the rules of probability. The observed results are usually slightly different from the expected results.
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PROBABILITY ____________________ is the __________ that a particular _________________ likelihood event will occur It can be written as a: Fraction ____ Percent ____ Ratio ____ 1/4 25% 1:3
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COIN FLIP 1/2 50% 1:1 There are 2 possible outcomes: HEADS TAILS
COIN FLIP There are 2 possible outcomes: HEADS TAILS The chance the coin will land on either one is: ____ ____ ____ Alleles segregate randomly just like a coin flip. . . So can use probability to predict outcomes of genetic crosses. 1/2 50% 1:1
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PROBABILITIES _____ outcomes ______ affect _________ones
_____________works ______ in ___________ a ________ number of events. PAST DON’T FUTURE If last coin flip was heads… there is still a 50/50 chance the next flip will be heads too. Probability predicting best large The more flips. . . The closer results will be to the expected 50:50 average.
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DIHYBRID CROSSES (2 traits)
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Mendel also asked the question?
Does the gene that determines if a seed is round or wrinkled have anything to do with the gene for seed shape? Must a seed that is yellow also be round?
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MAKING A CROSS with ___________________= ____________________
TWO gene traits DIHYBRID CROSS A Punnett square for a DIHYBRID CROSS looks like this:
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Figure 11-10 Independent Assortment in Peas
Section 11-3
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LET’S MAKE A DIHYBRID CROSS
HOMOZYGOUS YELLOW ROUND HOMOZYGOUS GREEN WRINKLED rryy RRYY 1. ___________ what _________________ are 2. ________correct__________ square __________ 3. ______ possible_______________________ 4. ______ boxes with _____________________ 5. Determine ____________of_____________& ____________ Figure out parent alleles Choose Punnett size Put in parent gametes Fill in offspring combinations probabilities phenotypes genotypes
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LAW OF __________________________
the factors are distributed to gametes independently of other factors INDEPENDENT ASSORTMENT Image modified from:
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PRACTICE MAKING GAMETES
WHAT ARE THE POSSIBLE GAMETES THIS PARENT CAN MAKE? HOMOZYGOUS ROUND YELLOW Each gamete should get one of each kind of gene R R Y Y R Y R Y R Y R Y ___________ ____________ _____________ _____________
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PRACTICE MAKING GAMETES
WHAT ARE THE POSSIBLE GAMETES THIS PARENT CAN MAKE? Each gamete should get one of each kind of gene HOMOZYGOUS WRINKLED GREEN r r y y r y r y r y r y ___________ ____________ _____________ _____________
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PRACTICE MAKING GAMETES
WHAT ARE THE POSSIBLE GAMETES THIS PARENT CAN MAKE? HETEROZYGOUS ROUND YELLOW Each gamete should get one of each kind of gene R r Y y R Y r y r Y R y ___________ ____________ _____________ _____________
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RY RrYy ROUND YELLOW ry 100% of offspring = _______ genotype
RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy RrYy 100% of offspring = _______ genotype _______________________ phenotype ROUND YELLOW
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X R r Y y R r Y y MAKE ANOTHER CROSS HETEROZYGOUS ROUND YELLOW
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POSSIBLE PARENT GAMETES?
RY ry rY Ry
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heterozygous dihybrid 9:3:3:1
RY Ry rY ry ____ Round & Yellow ____ Round & green ____ Wrinkled & yellow ____ wrinkled & green 9 RY Ry rY ry RRYY RRYy RrYY RrYy RRYy RRyy RrYy Rryy RrYY RrYy rrYY rrYy RrYy Rryy rrYy rryy 3 3 1 heterozygous dihybrid Sign of a ______________________ cross is a _____________ ratio in offspring. 9:3:3:1
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__________ratio is a clue that it’s a
9 ____ ____________ TRAIT 1 ; ____________ TRAIT 2 ____ ____________ TRAIT 1; _____________ TRAIT 2 ____ ____________ TRAIT 1; _____________ TRAIT 2 dominant dominant 3 dominant recessive 3 recessive dominant 1 recessive recessive __________ratio is a clue that it’s a ____________________________cross 9:3:3:1 HETEROZYGOUS TWO gene
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PRACTICE MAKING GAMETES for DIHYBRID CROSSES
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What are the possible gametes?
R R T T pure round & pure tall = __________ ____ ____ _____ ______ What gametes can it produce? R T R T R T R T
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What are the possible gametes?
T t R R Heterozygous Tall = __________ & pure round ____ ____ _____ ______ What gametes can it produce? T R t R t R T R
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What are the possible gametes?
T t r r Hybrid tall = __________ & pure wrinkled ____ ____ _____ ______ What gametes can it produce? T r t r t r T r
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What are the possible gametes?
T t R r Heterozygous tall = __________ & hybrid round ____ ____ _____ ______ What gametes can it produce? T R t r t R T r
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Section 11.1 Read section 11.1 as a review
Complete Practice 1 and Practice 2
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Exploring Mendelian Genetics 11-3
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GENES are more complicated than Mendel thought
ENVIRONMENT influences ____________________________ the ________________________. = ________________________ Genes ________ the ______ for development, but how plan unfolds also _______ on ______________conditions. expression of genes “Nature vs Nurture” provide plan depends environmental
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GENES are more complicated than Mendel thought
Some traits have ____________ allele __________ = ____________________ EX: blood type Allele choices ___ ___ ___ choices MORE than 2 MULTIPLE ALLELE TRAIT A B O
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GENES are more complicated than MENDEL thought
Some traits are determined by ____________________________ = __________________ EX: human height intelligence, skin & eye color MORE THAN ONE GENE POLYGENIC TRAIT
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GENES are more complicated than MENDEL thought
Traits determined by ____________ _________ have _____ “___________” phenotypes MORE than ONE gene many in-between There aren’t just SMART people and DUMB people…. there is a ________________ of intelligences in-between whole range
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GENES are more complicated than MENDEL thought
KINDS OF DOMINANCE ____________________ COMPLETE DOMINANCE INCOMPLETE DOMINANCE CO-DOMINANCE
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COMPLETE DOMINANCE Dominant masks recessive Recessive returns 3:1 F2
__________ allele _______ the ___________ one PATTERN ? ____________ allele ________ in a _____ratio in the ____ generation Recessive returns 3:1 F2
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INCOMPLETE DOMINANCE DON’T SEE __________ expected _____ ratio in
F2 generation _____________ organisms with one dominant and one recessive allele show a _________ in-between trait 3:1 Heterozygous BLENDED Image modified from:
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CO-DOMINANCE BOTH _______ traits are expressed at ___________ (_____________________) in heterozygote SAME TIME NO BLENDING ROAN A ________HORSE has ______________ hair and __________ hair side by side BOTH RED WHITE
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CO-DOMINANCE Both traits are expressed together (NO BLENDING) in heterozygote Sickle Cell Anemia Heterozygous- no problems Homozygous-
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Membrane proteins with _______ attached that help cells recognize self
REMEMBER Membrane proteins with _______ attached that help cells recognize self = ______________ sugars GLYCOPROTEINS
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The pattern of sugars that is attached is determined by genes
BLOOD TYPES have more than 2 allele choices = _________________________ MULTIPLE ALLELE TRAIT The pattern of sugars that is attached is determined by genes Allele choices are: _____ ____ ____ A B O
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BLOOD TYPES An A allele tells the cell to put “A” glycoproteins
on its surface
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BLOOD TYPES A B allele tells the cell to put a
different “B” glycoprotein on its surface
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BLOOD TYPES An O allele tells
the cell NOT to put anything on the surface
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A and B are CO-DOMINANT A cell with BOTH an A and a B allele has BOTH
glycoproteins on its surface
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PHENOTYPE (BLOOD TYPE)
BLOOD TYPES & ALLELES GENOTYPE PHENOTYPE (BLOOD TYPE) AA AO BB BO OO AB A A B B O AB
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A and AB see A as “like me” as Different!
DONOR BLOOD A and AB see A as “like me” B and O see A as Different! IMMUNE SYSTEM ATTACKS! Body images modified from:
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B and AB see B as “like me” as Different!
DONOR BLOOD B and AB see B as “like me” A and O see B as Different! IMMUNE SYSTEM ATTACKS! Body images modified from:
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O ____ can donate to EVERY BLOOD TYPE = _____________________
DONOR BLOOD O ____ can donate to EVERY BLOOD TYPE = _____________________ Nothing on surface to recognize as “NOT SELF” UNIVERSAL DONOR YOU DON’T HAVE ANYTHING I DON’T HAVE! Body images modified from:
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Only AB sees AB as “like me”
DONOR BLOOD Only AB sees AB as “like me” A, B, and O see AB as Different! IMMUNE SYSTEM ATTACKS! Body images modified from:
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AB can only GIVE to AB BUT . . .
______ can RECEIVE FROM EVERY BLOOD TYPE = ________________________ UNIVERSAL RECIPIENT Body image modified from:
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BLOOD TYPE FREQUENCY IN USA
40% B 10% AB 4% O 46%
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ABO SYSTEM is NOT THE ONLY ONE
Rh Rh-
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OTHER BLOOD TYPES ____________________ IF: NO PROBLEMS
MOM is _____ & BABY is ____ Rh+ Rh+ MOM is _____ & BABY is _____ Rh+ Rh- Image modified from:
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Can be a ___________ IF: Mom is _____ Baby is _____
PROBLEM Can be a ___________ IF: Mom is _____ Baby is _____ Rh- Rh+ 1st baby OK but few baby cells entering mom’s bloodstream put mom’s immune system on alert for + cells. Next + baby, mom’s immune system can attack baby as it is growing Mom given shot after 1st birth prevents this Image modified from:
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Section 11.2 Complete Practice Questions
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