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Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting Anthony P. Furnary, MDa,d, Guangqiang Gao, MDa, Gary L. Grunkemeier, PhDb, YingXing Wu, MDb, Kathryn J. Zerr, MBAb, Stephen O. Bookin, MDc, H.Storm Floten, MDa,d, Albert Starr, MDa,d The Journal of Thoracic and Cardiovascular Surgery Volume 125, Issue 5, Pages (May 2003) DOI: /mtc Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions
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Left to right: Grunkemeier, Furnary (back row); Wu, Gao, Zerr (front row)
The Journal of Thoracic and Cardiovascular Surgery , DOI: ( /mtc ) Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions
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Fig. 1 Scattergram of average postoperative glucose levels of all 3554 patients with DM undergoing CABG according to date of surgery. Smoothed local regression (Loess) curve is superimposed. Initiation of Portland protocol is marked by vertical line. Note gradual reduction of glucose levels with time. The Journal of Thoracic and Cardiovascular Surgery , DOI: ( /mtc ) Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions
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Fig. 2 Mortality among patients with DM undergoing CABG by glucose quantile. Total bar heights represent overall mortality in each quantile. Note increase in overall mortality is overwhelmingly accounted for by increase in cardiac-related mortality. The Journal of Thoracic and Cardiovascular Surgery , DOI: ( /mtc ) Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions
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Fig. 3 Annualized mortality in all patients undergoing CABG (with DM, filled diamonds, vs without DM, open circles) during study years. Mortality in group without DM has not changed with time. However, mortality in group with DM has decreased dramatically. There is currently ( ) no statistical difference between these two groups. The Journal of Thoracic and Cardiovascular Surgery , DOI: ( /mtc ) Copyright © 2003 American Association for Thoracic Surgery Terms and Conditions
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